Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta [154-461]'
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20024BDBM20024(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 1.40nM EC50:  316nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20015BDBM20015(2-[4-({[3-(3-benzyl-8-chloroquinolin-4-yl)phenyl]a...)
Affinity DataIC50: 1.40nM EC50:  23nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20001BDBM20001(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 1.90nM EC50:  33nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35107BDBM35107(biarylether amide quinoline, 4g)
Affinity DataIC50: 1.90nM EC50:  138nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20001BDBM20001(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 1.90nM EC50:  33nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20000BDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 2nM EC50:  90nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20001BDBM20001(2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 2nM EC50:  90nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35094BDBM35094(biarylether alcohol quinoline, 5f)
Affinity DataIC50: 2.10nM EC50:  233nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20000BDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 2.10nM EC50:  71nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20000BDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 2.10nM EC50:  93nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20000BDBM20000(CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...)
Affinity DataIC50: 2.10nM EC50:  71nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20004BDBM20004(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 2.40nM EC50:  29nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35099BDBM35099(biarylether alcohol quinoline, 5i)
Affinity DataIC50: 2.5nM EC50:  108nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35105BDBM35105(biarylether amide quinoline, 4e)
Affinity DataIC50: 2.60nM EC50:  98nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20020BDBM20020(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 2.60nM EC50:  58nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20014BDBM20014(2-[4-({[3-(3-benzoyl-8-chloroquinolin-4-yl)phenyl]...)
Affinity DataIC50: 2.70nM EC50:  39nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35104BDBM35104(biarylether amide quinoline, 4d)
Affinity DataIC50: 2.80nM EC50:  144nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35106BDBM35106(biarylether amide quinoline, 4f)
Affinity DataIC50: 2.90nM EC50:  170nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35113BDBM35113(biarylether amide quinoline, 4n)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35089BDBM35089(biarylether alcohol quinoline, 5b)
Affinity DataIC50: 3.30nM EC50:  31nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20006BDBM20006(2-{4-[({3-[3-phenyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 3.70nM EC50:  44nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20021BDBM20021(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 3.80nM EC50:  78nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20005BDBM20005(2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-...)
Affinity DataIC50: 4.30nM EC50:  100nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20011BDBM20011(2-[4-({[3-(3-benzyl-8-methylquinolin-4-yl)phenyl]a...)
Affinity DataIC50: 5nM EC50:  90nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 19999BDBM19999(2-(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50: 5nM EC50:  143nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20025BDBM20025(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 5.40nM EC50:  795nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20010BDBM20010(2-[4-({[3-(3-benzoyl-8-methylquinolin-4-yl)phenyl]...)
Affinity DataIC50: 5.5nM EC50:  61nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20016BDBM20016(2-{3-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 6nM EC50:  141nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35114BDBM35114(biarylether amide quinoline, 4o)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20002BDBM20002(CHEMBL216645 | 2-{4-[({3-[3-benzyl-8-(trifluoromet...)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35115BDBM35115(biarylether amide quinoline, 4p)
Affinity DataIC50: 7nM EC50:  572nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20023BDBM20023(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 7.80nM EC50:  2.40E+3nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35092BDBM35092(biarylether alcohol quinoline, 5e)
Affinity DataIC50: 8.30nM EC50:  1.01E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20022BDBM20022(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 8.5nM EC50:  4.00E+3nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35102BDBM35102(biarylether amide quinoline, 4b)
Affinity DataIC50: 8.5nM EC50:  1.53E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 19993BDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 9nM EC50:  170nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35108BDBM35108(biarylether amide quinoline, 4i)
Affinity DataIC50: 9nM EC50:  800nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 19993BDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 9nM EC50:  16nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35103BDBM35103(biarylether amide quinoline, 4c)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35091BDBM35091(biarylether alcohol quinoline, 5d)
Affinity DataIC50: 10nM EC50:  646nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 26065BDBM26065(2-[(2,4-dimethylphenyl)methyl]-3-(4-fluorophenyl)-...)
Affinity DataIC50: 10nM EC50:  990nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 19993BDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 10nM EC50:  16nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35088BDBM35088(biarylether alcohol quinoline, 5a)
Affinity DataIC50: 11.7nM EC50:  1.03E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 19992BDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 12nM EC50:  310nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 19992BDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataIC50: 12nM EC50:  410nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35098BDBM35098(biarylether alcohol quinoline, 5h)
Affinity DataIC50: 12nM EC50:  938nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20017BDBM20017(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Affinity DataIC50: 12nM EC50:  1.27E+3nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35112BDBM35112(biarylether amide quinoline, 4m)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 20027BDBM20027({4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50: 12.8nM EC50:  2.30E+3nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandChemical structure of BindingDB Monomer ID 35090BDBM35090(biarylether alcohol quinoline, 5c)
Affinity DataIC50: 14nM EC50:  210nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 90 total ) | Next | Last >>
Jump to: