Compile Data Set for Download or QSAR
Report error Found 1120 Enz. Inhib. hit(s) with Target = 'Plasmepsin I'
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323469BDBM50323469(KNI-10743 | (R)-3-((2S,3S)-3-(2-(4-((2-(dimethylam...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323472BDBM50323472(KNI-10742 | (R)-3-((2S,3S)-3-(2-(4-((2-aminoethyl)...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377588BDBM50377588(CHEMBL257594)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209553BDBM50209553(KNI-10232 | (R)-N-((1S,2R)-2-hydroxy-2,3-dihydro-1...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169098BDBM50169098(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169100BDBM50169100(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 912BDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169104BDBM50169104(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169103BDBM50169103(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323737BDBM50323737(N-((2S)-1-((2S)-6-amino-1-(4-(6-methoxyquinolin-8-...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of Plasmodium falciparum PLM2 using Lys-Glu-Phe-Val-Phe-NPhe-Ala-Leu-Lys as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 912BDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209559BDBM50209559((4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]am...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209559BDBM50209559((4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]am...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7977BDBM7977((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7977BDBM7977((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  0.5nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2006
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209559BDBM50209559((4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]am...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7977BDBM7977((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209559BDBM50209559((4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]am...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8007BDBM8007((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(2H-1,3-benzodioxol...)
Affinity DataKi:  0.5nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7974BDBM7974(CHEMBL113208 | (3S,4S)-N-[(1S)-1-{[(1S)-1-carbamoy...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of Plasmodium falciparum recombinant plasmepsin-2 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7974BDBM7974(CHEMBL113208 | (3S,4S)-N-[(1S)-1-{[(1S)-1-carbamoy...)
Affinity DataKi:  0.560nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7974BDBM7974(CHEMBL113208 | (3S,4S)-N-[(1S)-1-{[(1S)-1-carbamoy...)
Affinity DataKi:  0.560nM ΔG°:  -52.3kJ/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2006
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366912BDBM50366912(CHEMBL1790774)
Affinity DataIC50: 0.590nMAssay Description:In vitro concentration required for inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323737BDBM50323737(N-((2S)-1-((2S)-6-amino-1-(4-(6-methoxyquinolin-8-...)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323470BDBM50323470((R)-3-((2S,3S)-3-(2-(4-(2-(ethylamino)ethylamino)-...)
Affinity DataKi:  0.680nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 912BDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169106BDBM50169106(Pyridine-2-carboxylic acid ((S)-1-{(1S,2S)-1-(biph...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8005BDBM8005((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(4-acetylphenyl)pro...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8005BDBM8005((2R,3R,4R,5R)-2,5-bis({[(2E)-3-(4-acetylphenyl)pro...)
Affinity DataKi:  0.800nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 912BDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169098BDBM50169098(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169109BDBM50169109(Pyridine-2-carboxylic acid ((S)-1-{(1S,2S)-1-(3-br...)
Affinity DataKi:  1nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200018BDBM50200018((3S,4S)-4-((2S,3S)-2-(4-(4-((S)-((S)-1-(1-(4-(6-me...)
Affinity DataKi:  1nMAssay Description:Inhibition of Plasmodium falciparum recombinant PLM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169105BDBM50169105(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-butyl...)
Affinity DataKi:  1nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001073BDBM50001073(CHEMBL3236067)
Affinity DataKi:  1nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169100BDBM50169100(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169103BDBM50169103(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001072BDBM50001072(CHEMBL3236066)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323468BDBM50323468(KNI-10740 | (R)-3-((2S,3S)-3-(2-(2,6-dimethyl-4-(m...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001070BDBM50001070(CHEMBL3236064)
Affinity DataKi:  1.20nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390636BDBM50390636(CHEMBL2069615)
Affinity DataKi:  1.30nMAssay Description:Inhibition of Plasmodium falciparum PLM2 using Lys-Glu-Phe-Val-Phe-NPhe-Ala-Leu-Lys as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8008BDBM8008((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  1.30nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8002BDBM8002((2R,3R,4R,5R)-N1,N6-Bis[(1S,2R)-2-hydroxy-1-indany...)
Affinity DataKi:  1.40nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595797BDBM50595797(CHEMBL5171401)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Plasmodium falciparum 3D7 HA-glms-tagged PMIX using DABCYL-HSFIQEGKEE-EDANS as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366909BDBM50366909(CHEMBL1790773)
Affinity DataIC50: 1.5nMAssay Description:In vitro concentration required for inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001069BDBM50001069(CHEMBL3236063)
Affinity DataKi:  1.70nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234547BDBM234547(US9353089, 304)
Affinity DataIC50: 1.88nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169104BDBM50169104(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-3-[(S)-...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169110BDBM50169110(Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-1-(biph...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390637BDBM50390637(CHEMBL2069616)
Affinity DataKi:  1.90nMAssay Description:Inhibition of Plasmodium falciparum PLM2 using Lys-Glu-Phe-Val-Phe-NPhe-Ala-Leu-Lys as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
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