Compile Data Set for Download or QSAR
Report error Found 481 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-2'
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069985BDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataKi:  1nMAssay Description:Inhibition of 20S immuno proteosome beta2i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Leu-al as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069985BDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataKi:  1nMAssay Description:Inhibition of 20s immunoproteasome beta2 trypsin-like activity in human spleen using Boc-Leu-Arg-Arg-AMC as substrate after 10 mins by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644998BDBM50644998(CHEMBL5571110)
Affinity DataKi:  2.40nMAssay Description:Inhibition of 20S proteasome beta-2 in human erythrocytes using Boc-LRR-AMC as substrate by AK-740 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517643BDBM50517643(CHEMBL4451682)
Affinity DataIC50: 5nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517609BDBM50517609(CHEMBL4440581)
Affinity DataIC50: 6nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517607BDBM50517607(CHEMBL4590398)
Affinity DataIC50: 7nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230543BDBM50230543(CHEMBL5283576)
Affinity DataIC50: 8nMAssay Description:Inhibition of beta2 proteasome (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398608BDBM50398608(MARIZOMIB)
Affinity DataIC50: 11nMAssay Description:Inhibition of 20S proteasome beta 2c (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426994BDBM50426994(CHEMBL2326533)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430961BDBM50430961(CHEMBL2337844)
Affinity DataIC50: 12nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426994BDBM50426994(CHEMBL2326533)
Affinity DataIC50: 13nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307481BDBM50307481((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Affinity DataIC50: 13nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307481BDBM50307481((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Affinity DataIC50: 13nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430968BDBM50430968(CHEMBL2337847)
Affinity DataIC50: 14nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430969BDBM50430969(CHEMBL2337846)
Affinity DataIC50: 15nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430970BDBM50430970(CHEMBL2337845)
Affinity DataIC50: 16nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185156BDBM50185156(Hmb-Val-Gln-Leu-VE | CHEMBL210439)
Affinity DataIC50: 20nMAssay Description:Inhibition of trypsin like activity of proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50430962BDBM50430962(CHEMBL2337843)
Affinity DataIC50: 20nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426996BDBM50426996(CHEMBL2326261)
Affinity DataIC50: 22nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526811BDBM50526811(Kzr-616)
Affinity DataIC50: 28nMAssay Description:Inhibition of 20S proteasome beta 2c (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398608BDBM50398608(MARIZOMIB)
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of human erythrocyte derived 20S proteasome subunit beta2 after 30 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536425BDBM50536425(CHEMBL4563298)
Affinity DataIC50: 29nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536425BDBM50536425(CHEMBL4563298)
Affinity DataIC50: 29nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398609BDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 20S proteasome beta 2c (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185159BDBM50185159(Hmb-Phe-Gln-Leu-VE | CHEMBL208162)
Affinity DataIC50: 32nMAssay Description:Inhibition of trypsin like activity of proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645001BDBM50645001(CHEMBL5573136)
Affinity DataKi:  36nMAssay Description:Inhibition of 20S proteasome beta-2 in human erythrocytes using Boc-LRR-AMC as substrate by AK-740 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185155BDBM50185155(H-Phe-Val-Gln-Leu-VE | CHEMBL207774)
Affinity DataIC50: 42nMAssay Description:Inhibition of trypsin like activity of proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536438BDBM50536438(CHEMBL4534488)
Affinity DataIC50: 45nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536431BDBM50536431(CHEMBL4519899)
Affinity DataIC50: 45nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536438BDBM50536438(CHEMBL4534488)
Affinity DataIC50: 45nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536438BDBM50536438(CHEMBL4534488)
Affinity DataIC50: 46nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536438BDBM50536438(CHEMBL4534488)
Affinity DataIC50: 46nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536431BDBM50536431(CHEMBL4519899)
Affinity DataIC50: 46nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517618BDBM50517618(CHEMBL4546121)
Affinity DataIC50: 46nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426992BDBM50426992(CHEMBL2326260)
Affinity DataIC50: 47nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426994BDBM50426994(CHEMBL2326533)
Affinity DataIC50: 50nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426997BDBM50426997(CHEMBL2326541)
Affinity DataIC50: 51nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069985BDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 52nMAssay Description:Inhibition of trypsin-like activity of 20S human proteasome assessed as Z-LRR-AMC hydrolysis at using Promega proteasome-Glo-3 substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  54nMAssay Description:Binding affinity to human PSMB2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536431BDBM50536431(CHEMBL4519899)
Affinity DataIC50: 60nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536431BDBM50536431(CHEMBL4519899)
Affinity DataIC50: 60nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536429BDBM50536429(CHEMBL4581491)
Affinity DataIC50: 63nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536429BDBM50536429(CHEMBL4581491)
Affinity DataIC50: 63nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517596BDBM50517596(CHEMBL4450505)
Affinity DataIC50: 65nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307481BDBM50307481((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Affinity DataIC50: 66nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536429BDBM50536429(CHEMBL4581491)
Affinity DataIC50: 66nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536429BDBM50536429(CHEMBL4581491)
Affinity DataIC50: 66nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307481BDBM50307481((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...)
Affinity DataIC50: 67nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50517610BDBM50517610(CHEMBL4545073)
Affinity DataIC50: 77nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644999BDBM50644999(CHEMBL5571666)
Affinity DataKi:  78nMAssay Description:Inhibition of 20S proteasome beta-2 in human erythrocytes using Boc-LRR-AMC as substrate by AK-740 assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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