Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase [325-648]'
LigandChemical structure of BindingDB Monomer ID 202665BDBM202665(US9694016, 10 | US9242969, 10 | US10245267, Exampl...)
Affinity DataIC50: 0.118nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202696BDBM202696(US9694016, 42 | US9242969, 42 | US10245267, Exampl...)
Affinity DataIC50: 0.137nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202656BDBM202656(US9694016, 1 | US9242969, 1 | US10245267, Example ...)
Affinity DataIC50: 0.144nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202772BDBM202772(US9694016, 119 | US9242969, 119 | US10245267, Exam...)
Affinity DataIC50: 0.270nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202771BDBM202771(US9694016, 118 | US9242969, 118 | US10245267, Exam...)
Affinity DataIC50: 0.308nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202697BDBM202697(US9242969, 43 | US10245267, Example 42 | US1070971...)
Affinity DataIC50: 0.376nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202718BDBM202718(US9694016, 111 | US9242969, 64 | US10245267, Examp...)
Affinity DataIC50: 0.403nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202661BDBM202661(US9694016, 6 | US9242969, 6 | US10245267, Example ...)
Affinity DataIC50: 0.408nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202845BDBM202845(US9694016, 198 | US9242969, 198 | US10245267, Exam...)
Affinity DataIC50: 0.455nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202717BDBM202717(US9694016, 63 | US9242969, 63 | US10245267, Exampl...)
Affinity DataIC50: 0.508nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202663BDBM202663(US9694016, 8 | US9242969, 9 | US9242969, 8 | US107...)
Affinity DataIC50: 0.514nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202668BDBM202668(US9694016, 13 | US9242969, 13 | US10245267, Exampl...)
Affinity DataIC50: 0.533nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202666BDBM202666(US9694016, 11 | US9242969, 11 | US10245267, Exampl...)
Affinity DataIC50: 0.580nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202843BDBM202843(US9694016, 196 | US9242969, 196 | US10245267, Exam...)
Affinity DataIC50: 0.621nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202698BDBM202698(US9694016, 44 | US9242969, 44 | US10245267, Exampl...)
Affinity DataIC50: 0.714nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202669BDBM202669(US9694016, 14 | US9242969, 14 | US10245267, Exampl...)
Affinity DataIC50: 0.803nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202764BDBM202764(US9694016, 64 | US9242969, 111 | US10245267, Examp...)
Affinity DataIC50: 0.847nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 77059BDBM77059(US9694016, 9 | US10245267, Example 9 | US10709712,...)
Affinity DataIC50: 0.899nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202699BDBM202699(US9694016, 45 | US9242969, 45 | US10245267, Exampl...)
Affinity DataIC50: 1.02nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202662BDBM202662(US9694016, 7 | US9242969, 7 | US10245267, Example ...)
Affinity DataIC50: 1.11nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202846BDBM202846(US9694016, 199 | US9242969, 199 | US10245267, Exam...)
Affinity DataIC50: 1.29nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 202657BDBM202657(US9694016, 2 | US9242969, 2 | US10709712, Example ...)
Affinity DataIC50: 2.95nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent