Compile Data Set for Download or QSAR
Report error Found 293 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3'
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196843BDBM50196843(CHEMBL3904640)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381682BDBM381682(US10272079, Compound 005 | US10272079, Compound 39)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human NHE3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381823BDBM381823(US10272079, Compound 002 | US10272079, Compound 18...)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601173BDBM50601173(CHEMBL5176968)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601180BDBM50601180(CHEMBL5170002)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381826BDBM381826(US10272079, Compound 003)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196811BDBM50196811(CHEMBL3967635)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601178BDBM50601178(CHEMBL5202545)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471224BDBM50471224(CHEMBL64889)
Affinity DataIC50: 2nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 381826BDBM381826(US10272079, Compound 003)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426615BDBM426615(N,N′-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196812BDBM50196812(CHEMBL3946835)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196805BDBM50196805(CHEMBL3978001)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601172BDBM50601172(CHEMBL5183104)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471235BDBM50471235(CHEMBL416314)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471210BDBM50471210(CHEMBL292311)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471144BDBM50471144(CHEMBL60551)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471218BDBM50471218(CHEMBL59697)
Affinity DataIC50: 6nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196829BDBM50196829(CHEMBL3914729)
Affinity DataIC50: 6nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601178BDBM50601178(CHEMBL5202545)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471196BDBM50471196(CHEMBL292105)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601181BDBM50601181(CHEMBL5170188)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426616BDBM426616(N,N′-(2,2′-(2,2′-(2,2′-(1,...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601179BDBM50601179(CHEMBL5202068)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471187BDBM50471187(CHEMBL303354)
Affinity DataIC50: 8nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058715BDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 8nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058715BDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 8nMAssay Description:Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471246BDBM50471246(CHEMBL302450)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471189BDBM50471189(CHEMBL302222)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471251BDBM50471251(CHEMBL60249)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471203BDBM50471203(CHEMBL62461)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471202BDBM50471202(CHEMBL61271)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471167BDBM50471167(CHEMBL294310)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601180BDBM50601180(CHEMBL5170002)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601179BDBM50601179(CHEMBL5202068)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471229BDBM50471229(CHEMBL64359)
Affinity DataIC50: 10nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196789BDBM50196789(CHEMBL3892788)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471152BDBM50471152(CHEMBL64611)
Affinity DataIC50: 11nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196842BDBM50196842(CHEMBL3943277)
Affinity DataIC50: 11nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471248BDBM50471248(CHEMBL291658)
Affinity DataIC50: 11nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471188BDBM50471188(CHEMBL64873)
Affinity DataIC50: 12nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471216BDBM50471216(CHEMBL62385)
Affinity DataIC50: 12nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 426507BDBM426507(N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50: 13nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601181BDBM50601181(CHEMBL5170188)
Affinity DataIC50: 13nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471819BDBM50471819(CHEMBL332433)
Affinity DataIC50: 13nMAssay Description:Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471244BDBM50471244(CHEMBL305087)
Affinity DataIC50: 13nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471200BDBM50471200(CHEMBL294316)
Affinity DataIC50: 14nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471148BDBM50471148(CHEMBL418505)
Affinity DataIC50: 14nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471814BDBM50471814(CHEMBL126367)
Affinity DataIC50: 14nMAssay Description:Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 3(Rabbit)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471159BDBM50471159(CHEMBL302914)
Affinity DataIC50: 14nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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