Compile Data Set for Download or QSAR
Report error Found 1768 Enz. Inhib. hit(s) with Target = 'Substance-K receptor'
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476247BDBM50476247(CHEMBL224081)
Affinity DataKi:  0.0251nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404016BDBM50404016(CHEMBL2112922)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]NKA from human Tachykinin receptor 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415924BDBM50415924(CHEMBL1083850)
Affinity DataKi:  0.0501nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404016BDBM50404016(CHEMBL2112922)
Affinity DataKi:  0.0501nMAssay Description:Displacement of [125I]NKA from human Tachykinin receptor 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476235BDBM50476235(CHEMBL436981)
Affinity DataKi:  0.0501nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476788BDBM50476788(CHEMBL243711)
Affinity DataKi:  0.0525nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476771BDBM50476771(CHEMBL244362)
Affinity DataKi:  0.0575nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476748BDBM50476748(CHEMBL395972)
Affinity DataKi:  0.0603nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476233BDBM50476233(CHEMBL439281)
Affinity DataKi:  0.0631nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476221BDBM50476221(CHEMBL387506)
Affinity DataKi:  0.0631nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476750BDBM50476750(Ibodutant | MEN-15596)
Affinity DataKi:  0.0759nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366377BDBM50366377(MEN-10627 | CHEMBL334721)
Affinity DataIC50: 0.0790nMAssay Description:Tested for binding affinity of compound against [125I]NKA binding to neurokinin-2 (NK-2) receptor in hamster urinary bladderMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415954BDBM50415954(CHEMBL1083858)
Affinity DataKi:  0.0794nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415966BDBM50415966(CHEMBL1083974)
Affinity DataKi:  0.0794nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476764BDBM50476764(CHEMBL395974)
Affinity DataKi:  0.0977nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50472916BDBM50472916(CHEMBL223221 | MEN-11690)
Affinity DataKi:  0.100nMAssay Description:Inhibitory affinity constant (pKi) against tachykinin receptor 2 (NK-2R) using heterologous competition experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476219BDBM50476219(CHEMBL225297)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415928BDBM50415928(CHEMBL1083879)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476250BDBM50476250(CHEMBL389510)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)TBA
LigandChemical structure of BindingDB Monomer ID 50212987BDBM50212987(CHEMBL2110370 | GR-159897)
Affinity DataKi:  0.100nMAssay Description:Binding affinity by displacement of radiolabeled GR-100679 from Tachykinin receptor 2 from homogenized rat colonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2018
Entry Details

TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50472916BDBM50472916(CHEMBL223221 | MEN-11690)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50472916BDBM50472916(CHEMBL223221 | MEN-11690)
Affinity DataKi:  0.100nMAssay Description:Binding affinity towards Tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476754BDBM50476754(CHEMBL242626)
Affinity DataKi:  0.117nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476229BDBM50476229(CHEMBL224374)
Affinity DataKi:  0.126nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476251BDBM50476251(CHEMBL224003)
Affinity DataKi:  0.126nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404025BDBM50404025(CHEMBL2112925)
Affinity DataKi:  0.126nMAssay Description:Displacement of [125I]NKA from human Tachykinin receptor 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415943BDBM50415943(CHEMBL1083869)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415949BDBM50415949(CHEMBL1083863)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50071484BDBM50071484(N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476793BDBM50476793(CHEMBL394780)
Affinity DataKi:  0.132nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476753BDBM50476753(CHEMBL395973)
Affinity DataKi:  0.141nMAssay Description:Displacement of [125I]neurokinin A from human recombinant NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048413BDBM50048413(CHEMBL2370064)
Affinity DataKi:  0.155nMAssay Description:Displacement of [3H]GR100679 from NK2 receptor (unknown origin) expressed in CHO/T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469874BDBM50469874(CHEMBL59780)
Affinity DataKi:  0.155nMAssay Description:Binding affinity against human NK2 receptors expressed in CHO cells using [3H]GR-100679 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415938BDBM50415938(CHEMBL1083875)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415939BDBM50415939(CHEMBL1083874)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415970BDBM50415970(CHEMBL1083870)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415940BDBM50415940(CHEMBL1083873)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]neurokinin A from human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476223BDBM50476223(CHEMBL413715)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473829BDBM50473829(MEN-11995 | CHEMBL389459)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50473829BDBM50473829(MEN-11995 | CHEMBL389459)
Affinity DataKi:  0.158nMAssay Description:Inhibitory affinity constant (pKi) against tachykinin receptor 2 (NK-2R) using heterologous competition experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476231BDBM50476231(CHEMBL225588)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476222BDBM50476222(CHEMBL266284)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476244BDBM50476244(CHEMBL389511)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476236BDBM50476236(CHEMBL224009)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476220BDBM50476220(CHEMBL225392)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476256BDBM50476256(CHEMBL388626)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476253BDBM50476253(CHEMBL389279)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]neurokinin A from human NK2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116745BDBM50116745(N-{(R)-5-[4-(3-Carbamoylmethyl-2-oxo-tetrahydro-py...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]-NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Guinea pig)
The Schering Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116083BDBM50116083(3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-5-(3-dimet...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding to Tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 97486BDBM97486(US8470816, 464)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
US Patent

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