Compile Data Set for Download or QSAR
Report error Found 514 Enz. Inhib. hit(s) with Target = 'Tryptase'
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083552BDBM50083552(1,9-di{4-[5-amino(imino)methylbenzo[b]furan-2-ylca...)
Affinity DataKi:  0.0190nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083561BDBM50083561(1-{4-[5-amino(imino)methylbenzo[b]thiophen-2-ylcar...)
Affinity DataKi:  0.0280nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083556BDBM50083556(1-{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbon...)
Affinity DataKi:  0.0290nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083541BDBM50083541(1-{4-[5-amino(imino)methyl-4,5,6,7-tetrahydrothien...)
Affinity DataKi:  0.0460nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083548BDBM50083548(1-{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbon...)
Affinity DataKi:  0.0570nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093142BDBM50093142(APC-1390 | 1N-(3,3-diphenylpropyl)-4-[4-amino(imin...)
Affinity DataKd:  0.0700nMAssay Description:Dissociation constant of compound was evaluated from its IC50 against tryptase at different concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093142BDBM50093142(APC-1390 | 1N-(3,3-diphenylpropyl)-4-[4-amino(imin...)
Affinity DataKd:  0.0700nMAssay Description:Dissociation constant of compound was evaluated from its IC50 against tryptase at different concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218667BDBM50218667(APC-1390 | CHEMBL46809)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093142BDBM50093142(APC-1390 | 1N-(3,3-diphenylpropyl)-4-[4-amino(imin...)
Affinity DataKi:  0.0700nMAssay Description:Inhibitory activity against human tryptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093175BDBM50093175(Derivative of APC-2059 | CHEMBL311655)
Affinity DataKi:  0.100nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093157BDBM50093157(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  0.100nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase gamma(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093153BDBM50093153(Derivative of APC-2059 | CHEMBL306620)
Affinity DataKd:  0.100nMAssay Description:Dissociation constant of compound was evaluated from its IC50 against tryptase at different concentrationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217306BDBM50217306(CHEMBL112049)
Affinity DataKi:  0.120nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093192BDBM50093192(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  0.200nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093167BDBM50093167(Derivative of APC-2059 | CHEMBL75750)
Affinity DataKi:  0.400nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093156BDBM50093156(Derivative of APC-2059 | CHEMBL432172)
Affinity DataKi:  0.400nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093154BDBM50093154(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  0.400nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217812BDBM50217812(CHEMBL322526)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101018BDBM50101018(1,4-di{4-[4-amino(imino)methylphenylcarboxamidomet...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity against human tryptase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101018BDBM50101018(1,4-di{4-[4-amino(imino)methylphenylcarboxamidomet...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093199BDBM50093199(Derivative of APC-2059 | CHEMBL75972)
Affinity DataKi:  0.5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218668BDBM50218668(CHEMBL42900)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093173BDBM50093173(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  0.5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093158BDBM50093158(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  0.5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084616BDBM50084616([(4-Aminomethyl-benzylcarbamoyl)-methyl]-carbamic ...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217626BDBM50217626(CHEMBL322538)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093178BDBM50093178(Derivative of APC-2059 | CHEMBL76883)
Affinity DataKi:  0.700nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217627BDBM50217627(CHEMBL110061)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101011BDBM50101011(1,5-di{4-[4-amino(imino)methylphenylcarboxamidomet...)
Affinity DataKi:  0.850nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101019BDBM50101019(1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydr...)
Affinity DataKi:  0.910nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093176BDBM50093176(Derivative of piperazine-1-carboxylic acid 5-(pipe...)
Affinity DataKi:  1nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217599BDBM50217599(CHEMBL109888)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217801BDBM50217801(CHEMBL111250)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217622BDBM50217622(CHEMBL443539)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144582BDBM50144582((R)-1-[4-(6-Naphthalen-2-yl-hexanoyl)-piperazine-1...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144577BDBM50144577((R)-1-[4-(6-Naphthalen-1-yl-hexanoyl)-piperazine-1...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144555BDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144535BDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144535BDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144586BDBM50144586((R)-1-[4-(7-Naphthalen-1-yl-heptanoyl)-piperazine-...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083549BDBM50083549(1-{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbon...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of tryptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101016BDBM50101016(1-{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydr...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Tryptase in human mast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156461BDBM50156461(3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156460BDBM50156460(3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbonyl]...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221046BDBM50221046(CHEMBL72282)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217818BDBM50217818(CHEMBL440515)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217822BDBM50217822(CHEMBL111173)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120387BDBM50120387(BMS-363131 | (2S,3R)-3-((R)-1-Carbamimidoyl-piperi...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTryptase delta(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120387BDBM50120387(BMS-363131 | (2S,3R)-3-((R)-1-Carbamimidoyl-piperi...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details Article
PubMed
TargetTryptase beta-2/delta/gamma(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217824BDBM50217824(BMS-363130 | CHEMBL70738)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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