Compile Data Set for Download or QSAR
Report error Found 285 Enz. Inhib. hit(s) with Target = 'VHL complex'
TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454848BDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50: 16.3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560814BDBM560814(US11389438, # 54)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560701BDBM560701(US11389438, # 11)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560818BDBM560818(US11389438, # 58)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560712BDBM560712(US11389438, # 44)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560809BDBM560809(US11389438, # 45)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560711BDBM560711(US11389438, # 43)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560812BDBM560812(US11389438, # 48)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560810BDBM560810(US11389438, # 46)
Affinity DataKd: <50nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454972BDBM454972(US10730870, Example 141 | US11512083, Example 141)
Affinity DataIC50: 70.9nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560816BDBM560816(US11389438, # 56)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560702BDBM560702(US11389438, # 20)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560817BDBM560817(US11389438, # 57)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560703BDBM560703(US11389438, # 21)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560700BDBM560700(US11389438, # 3)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560815BDBM560815(US11389438, # 55)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560709BDBM560709(US11389438, # 25)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560698BDBM560698(US11389438, # 1)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560699BDBM560699(US11389438, # 2)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560813BDBM560813(US11389438, # 53)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560811BDBM560811(US11389438, # 47)
Affinity DataKd:  75nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454969BDBM454969(US10730870, Example 138 | US10730870, Example 145 ...)
Affinity DataIC50: 100nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454909BDBM454909(US10730870, Example 76 | US11512083, Example 76)
Affinity DataIC50: 169nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454884BDBM454884(US10730870, Example 47 | US11512083, Example 47)
Affinity DataIC50: 178nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454907BDBM454907(US10730870, Example 74 | US11512083, Example 74)
Affinity DataIC50: 264nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454853BDBM454853(US10730870, Example 16 | US11512083, Example 16)
Affinity DataIC50: 265nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454897BDBM454897(US10730870, Example 60 | US11512083, Example 60)
Affinity DataIC50: 293nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560707BDBM560707(US11389438, # 24)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560705BDBM560705(US11389438, # 22)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560706BDBM560706(US11389438, # 23)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 560710BDBM560710(US11389438, # 26)
Affinity DataKd:  300nMAssay Description:Surface Plasmon Resonance (SPR) assays have been developed to test the affinity (KD) of VHL or CRBN-based compounds to respective recombinant ligase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454846BDBM454846(US10730870, Example 9 | US11512083, Example 9)
Affinity DataIC50: 309nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454854BDBM454854(US10730870, Example 17 | US11512083, Example 17)
Affinity DataIC50: 317nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454916BDBM454916(US10730870, Example 83 | US11512083, Example 83)
Affinity DataIC50: 320nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454884BDBM454884(US10730870, Example 47 | US11512083, Example 47)
Affinity DataIC50: 339nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454910BDBM454910(US10730870, Example 77 | US11512083, Example 77)
Affinity DataIC50: 349nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454881BDBM454881(US10730870, Example 44 | US11512083, Example 44)
Affinity DataIC50: 385nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454858BDBM454858(US10730870, Example 21 | US11512083, Example 21)
Affinity DataIC50: 392nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454932BDBM454932(US10730870, Example 99 | US11512083, Example 99)
Affinity DataIC50: 418nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454863BDBM454863(US10730870, Example 26 | US11512083, Example 26)
Affinity DataIC50: 441nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454907BDBM454907(US10730870, Example 74 | US11512083, Example 74)
Affinity DataIC50: 450nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454881BDBM454881(US10730870, Example 44 | US11512083, Example 44)
Affinity DataIC50: 465nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454890BDBM454890(US10730870, Example 53 | US11512083, Example 53)
Affinity DataIC50: 474nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454846BDBM454846(US10730870, Example 9 | US11512083, Example 9)
Affinity DataIC50: 498nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454872BDBM454872(US10730870, Example 35 | US11512083, Example 35)
Affinity DataIC50: 509nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454839BDBM454839(US10730870, Example 2 | US11512083, Example 2)
Affinity DataIC50: 533nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454870BDBM454870(US10730870, Example 33 | US11512083, Example 33)
Affinity DataIC50: 539nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454848BDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50: 542nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454910BDBM454910(US10730870, Example 77 | US11512083, Example 77)
Affinity DataIC50: 550nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetVHL complex(Human)
Arvinas Operations

US Patent
LigandChemical structure of BindingDB Monomer ID 454927BDBM454927(US10730870, Example 94 | US11512083, Example 94)
Affinity DataIC50: 566nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

Displayed 1 to 50 (of 285 total ) | Next | Last >>
Jump to: