Affinity DataKi: 0.5nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 40) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Antagonist activity at ER in human Ishikawa cells assessed as inhibition of E2-induced alkaline phosphatase induction after 72 hrs by PNPP substrate ...More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Antagonist activity at ER in human MCF7 cells assessed as inhibition of 17beta-estradiol-induced cell proliferationMore data for this Ligand-Target Pair
Affinity DataKi: 4.31nMAssay Description:Inhibition of [125I]2-(3'-Iodo-4'-N-methylaminophenyl) benzothiazole binding to amyloid beta (1 to 40) (unknown origin) after 3 hrs by NaI well count...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of human erythrocytes mu-calpain using SucLeu-Tyr-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 912nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 912nMAssay Description:Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Binding affinity of the compound for hog liver Folyl-polyglutamate synthase was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.98E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.41E+5nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.89E+6nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Mus musculus)
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-BMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Mus musculus)
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Mus musculus)
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: <0.00200nMAssay Description:Displacement of [3H]17beta-estradiol from ER in human MCF7 cells after 18 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Mus musculus)
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
R.C. Patel Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0460nMAssay Description:Displacement of [3H]17beta-estradiol from ER in human MCF7 cells after 18 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair
TargetSUMO-activating enzyme subunit 1/2(Homo sapiens (Human))
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals, A Wholly Owned Subsidiary Of Takeda Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km...More data for this Ligand-Target Pair