Found 12 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50004774' 
Affinity DataKi: 0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of hepatic cells (HEP G2, a human hepatoma cell line)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of microsomal rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase from rat hepatocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
