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Found 300 with Last Name = 'sebastian' and Initial = 'a'
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85393(14β-(p-chlorocinnamoylamino)-7,8-dihydrocodei...)
Affinity DataKi:  0.120nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85396(CACO)
Affinity DataKi:  0.460nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOpioid receptor delta 1(Bos taurus)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85393(14β-(p-chlorocinnamoylamino)-7,8-dihydrocodei...)
Affinity DataKi:  0.75nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  0.900nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85393(14β-(p-chlorocinnamoylamino)-7,8-dihydrocodei...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85394(N-CPM-CACO)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85395(MC-CAM)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  2.29nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  2.30nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  6.62nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85394(N-CPM-CACO)
Affinity DataKi:  9.80nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOpioid receptor delta 1(Bos taurus)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85395(MC-CAM)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85395(MC-CAM)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOpioid receptor delta 1(Bos taurus)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85394(N-CPM-CACO)
Affinity DataKi:  16nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  17nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM85396(CACO)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  25.2nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  25.2nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  27.7nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  40.6nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  41nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050481(10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...)
Affinity DataKi:  52nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050481(10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...)
Affinity DataKi:  91.6nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi:  102nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  109nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  123nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  132nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050483(9,13-dimethyl-13-azatetracyclo[7.5.1.01,12.03,8]pe...)
Affinity DataKi:  179nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050483(9,13-dimethyl-13-azatetracyclo[7.5.1.01,12.03,8]pe...)
Affinity DataKi:  215nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  297nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  297nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  330nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi:  380nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi:  380nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  409nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050481(10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...)
Affinity DataKi:  459nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  467nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi:  650nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi:  795nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  830nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  830nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  863nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  1.40E+3nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  2.90E+3nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50050486(1-methoxymethyl-9-methyl-(1S,9R)-2,3,4,5-tetraazat...)
Affinity DataKi:  3.80E+3nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi: >5.00E+3nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050483(9,13-dimethyl-13-azatetracyclo[7.5.1.01,12.03,8]pe...)
Affinity DataKi: >1.00E+4nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  1.00E+4nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institute

Curated by ChEMBL
LigandPNGBDBM50050486(1-methoxymethyl-9-methyl-(1S,9R)-2,3,4,5-tetraazat...)
Affinity DataKi: >1.00E+4nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50050486(1-methoxymethyl-9-methyl-(1S,9R)-2,3,4,5-tetraazat...)
Affinity DataKi: >1.00E+4nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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