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Target
Kappa-type opioid receptor
Ligand
BDBM50050478
Substrate
n/a
Meas. Tech.
ChEMBL_145506 (CHEMBL752148)
Ki
409±n/a nM
Citation
 Schultz, AG; Wang, A; Alva, C; Sebastian, A; Glick, SD; Deecher, DC; Bidlack, JM Asymmetric syntheses, opioid receptor affinities, and antinociceptive effects of 8-amino-5,9-methanobenzocyclooctenes, a new class of structural analogues of the morphine alkaloids. J Med Chem 39:1956-66 (1996) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50050478
Synonyms:
10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-trien-4-ol | CHEMBL301421
Type:
Small organic molecule
Emp. Form.:
C17H25NO
Mol. Mass.:
259.3865
SMILES:
CN(C)C1CCC2(C)CC1(C)Cc1ccc(O)cc21 |TLB:1:3:8:18.12.11,THB:17:18:8:3.4.5|
Structure:
Search PDB for entries with ligand similarity: