Affinity DataKi: 0.300nM ΔG°: -56.5kJ/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.29nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -48.8kJ/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 6.62nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 9nM ΔG°: -47.8kJ/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 12nM ΔG°: -47.0kJ/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -46.8kJ/mole IC50: 12nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 18nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nM IC50: 31nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -45.6kJ/mole IC50: 29nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 22.1nMAssay Description:Displacement of [3H]-WIN-35428 from human DAT expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 22.1nMAssay Description:Displacement of [3H]WIN35428 from human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nM ΔG°: -45.1kJ/mole IC50: 51nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 25.2nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 25.2nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 27nM ΔG°: -44.9kJ/mole IC50: 47nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 27.7nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -44.8kJ/mole IC50: 49nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
Affinity DataKi: 33nM IC50: 69nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
Affinity DataKi: 40.6nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 45nM ΔG°: -43.6kJ/mole IC50: 80nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 45nMAssay Description:Displacement of [3H]WIN35428 from human recombinant dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 46nM IC50: 57nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 50nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research
Curated by PDSP Ki Database
Wyeth Research
Curated by PDSP Ki Database
Affinity DataKi: 53nMAssay Description:Displacement of [3H]WIN35428 from human recombinant dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair