TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 10.3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 11.4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 85.3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 91.4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 114nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 268nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 304nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 389nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 640nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 657nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 681nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 2.92E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 4.68E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-Universit£T Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.158nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluo...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluo...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity to human His-thr XIAP BIR3 (241 to 356) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluore...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to human His-thr XIAP BIR3 (241 to 356) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluore...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant GST-fused Dyrk2 expressed in Escherichia coli using Woodtide as substrate after 15 mins by P81 membrane assay in pres...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant Dyrk1B using Woodtide as substrate after 15 mins by P81 membrane assay in presence of [33P]-g-ATPMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluo...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Dyrk1A (unknown origin) using dynatide 3 as substrate after 10 mins by P81 membrane assay in presence of [33P]-g-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant His6-tagged Dyrk1A expressed in Escherichia coli using Woodtide as substrate after 15 mins by P81 membrane assay in p...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair