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Found 103 with Last Name = 'lopez' and Initial = 'b'
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50256745((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475107(CHEMBL179928)
Affinity DataIC50:  170nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475105(CHEMBL189605)
Affinity DataIC50:  200nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475147(CHEMBL185804)
Affinity DataIC50:  210nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475104(CHEMBL362085)
Affinity DataIC50:  240nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475152(CHEMBL188975)
Affinity DataIC50:  240nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475139(CHEMBL187192)
Affinity DataIC50:  250nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475145(CHEMBL187453)
Affinity DataIC50:  250nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475159(CHEMBL189864)
Affinity DataIC50:  300nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475146(CHEMBL189138)
Affinity DataIC50:  350nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475122(CHEMBL188715)
Affinity DataIC50:  350nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475124(CHEMBL188687)
Affinity DataIC50:  360nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  400nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475121(CHEMBL363735)
Affinity DataIC50:  410nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475109(CHEMBL185679)
Affinity DataIC50:  410nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475154(CHEMBL187967)
Affinity DataIC50:  440nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475108(CHEMBL180882)
Affinity DataIC50:  460nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535678(CHEMBL4439878)
Affinity DataIC50:  478nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535680(CHEMBL4452842)
Affinity DataIC50:  518nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475134(CHEMBL181855)
Affinity DataIC50:  530nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475131(CHEMBL364656)
Affinity DataIC50:  530nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475111(CHEMBL186038)
Affinity DataIC50:  560nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475123(CHEMBL189072)
Affinity DataIC50:  610nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475120(CHEMBL187388)
Affinity DataIC50:  620nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475151(CHEMBL186218)
Affinity DataIC50:  630nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475136(CHEMBL186516)
Affinity DataIC50:  750nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475140(CHEMBL426981)
Affinity DataIC50:  910nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475153(CHEMBL365095)
Affinity DataIC50:  910nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475150(CHEMBL365284)
Affinity DataIC50:  910nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475119(CHEMBL187977)
Affinity DataIC50:  930nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475103(CHEMBL360177)
Affinity DataIC50:  970nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475161(CHEMBL186419)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475155(CHEMBL189671)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475133(CHEMBL186420)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475143(CHEMBL364873)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475115(CHEMBL186217)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475114(CHEMBL188382)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM7470(3-Amino-4,5-di(2-furyl)-1H-pyrazolo[3,4-c]pyridazi...)
Affinity DataIC50:  1.50E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475112(CHEMBL363071)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475125(CHEMBL188611)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM7463(4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine |...)
Affinity DataIC50:  3.00E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475135(CHEMBL189040)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475106(CHEMBL188610)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM7476(3-Amino-5-phenyl-1H-pyrazolo[3,4-c]pyridazine | 5-...)
Affinity DataIC50:  4.00E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475157(CHEMBL187505)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Universidad San Pablo Ceu

LigandPNGBDBM7477(5-(furan-2-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine...)
Affinity DataIC50:  5.30E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50475128(CHEMBL186209)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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