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Found 47 with Last Name = 'kwong' and Initial = 'cd'
LigandPNGBDBM50289961(CHEMBL65376 | Pentanedioic acid furan-2-ylmethyl e...)
Affinity DataIC50:  290nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289957(CHEMBL304442 | Pentanedioic acid 4-((E)-2-nitro-vi...)
Affinity DataIC50:  420nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289964(CHEMBL63559 | Pentanedioic acid 4-methoxy-phenyl e...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203110(CHEMBL3914791)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203111(CHEMBL3968023)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203043(CHEMBL3896867)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203113(CHEMBL3889816)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202837(CHEMBL3941751)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203040(CHEMBL3932774)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203048(CHEMBL3984603)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50289963(CHEMBL3142195 | CHEMBL92506 | Pentanedioic acid (2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289961(CHEMBL65376 | Pentanedioic acid furan-2-ylmethyl e...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289957(CHEMBL304442 | Pentanedioic acid 4-((E)-2-nitro-vi...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289963(CHEMBL3142195 | CHEMBL92506 | Pentanedioic acid (2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202840(CHEMBL3904763)
Affinity DataIC50:  4.54E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50214741(CHEMBL65096)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203042(CHEMBL3923820)
Affinity DataIC50:  5.69E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289964(CHEMBL63559 | Pentanedioic acid 4-methoxy-phenyl e...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50214742(CHEMBL302905)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203044(CHEMBL3960953)
Affinity DataIC50:  9.74E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50214738(CHEMBL65594)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50214739(CHEMBL68413)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50214743(CHEMBL63650)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50214740(CHEMBL67009)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50214737(CHEMBL63772)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202835(CHEMBL3895295)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203049(CHEMBL3904207)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203041(CHEMBL3895818)
Affinity DataIC50: <1.36E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202838(CHEBI:67605 | Eupolauridine)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202880(CHEMBL3914880)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203046(CHEMBL3913215)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202841(CHEMBL3972163)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203038(CHEMBL3975075)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203037(CHEMBL3890769)
Affinity DataIC50:  3.44E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203039(CHEMBL3903152)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203045(CHEMBL3915026)
Affinity DataIC50:  4.16E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203047(CHEMBL3932850)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202834(CHEMBL3957092)
Affinity DataIC50:  4.84E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203050(CHEMBL3984682)
Affinity DataIC50:  4.99E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202863(CHEMBL3896944)
Affinity DataIC50:  5.36E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202895(CHEMBL3976611)
Affinity DataIC50:  6.99E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203066(CHEMBL3904846)
Affinity DataIC50:  7.05E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203112(CHEMBL3984838)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203051(CHEMBL3985749)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202839(CHEMBL3968109)
Affinity DataIC50:  1.27E+5nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50202836(CHEMBL3894198)
Affinity DataIC50:  1.36E+5nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50203067(CHEMBL3922223)
Affinity DataIC50:  2.42E+5nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed