TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-2 adrenergic receptor in calf lung membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-1 adrenergic receptor in dog heart.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-2 adrenergic receptor in calf lung membranes.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 19.6nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-2 adrenergic receptor in calf lung membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-2 adrenergic receptor in calf lung membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-1 adrenergic receptor in dog heart.More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-2 adrenergic receptor in calf lung membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-1 adrenergic receptor in dog heartMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-1 adrenergic receptor in dog heart.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Compound was tested for inhibition of [3H]dihydroalprenolol radioligand binding to Beta-1 adrenergic receptor in dog heart.More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair