Compile Data Set for Download or QSAR
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Found 32 with Last Name = 'garattini' and Initial = 'e'
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170869((E)-3-(4'-Hydroxy-biphenyl-4-yl)-acrylic acid | CH...)
Affinity DataEC50: >1.00E+5nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483551(CHEMBL1688193)
Affinity DataEC50:  380nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170872((E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)...)
Affinity DataEC50:  1.76E+4nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170887((E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)...)
Affinity DataEC50:  7.70E+3nMAssay Description:Binding affinity towards aldosterone receptor (Mineralocorticoid receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170866((E)-3-(3'-Cyclohexylmethyl-4'-hydroxy-biphenyl-4-y...)
Affinity DataEC50:  5.30E+3nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50170868((E)-3-(4'-Hydroxy-[1,1';3',1'']terphenyl-4-yl)-acr...)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483539(CHEMBL1688184)
Affinity DataEC50:  30nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483540(CHEMBL1688186)
Affinity DataEC50:  190nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483541(CHEMBL1688187)
Affinity DataEC50:  460nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483542(CHEMBL1688190)
Affinity DataEC50:  390nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483543(CHEMBL1688191)
Affinity DataEC50:  340nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483544(CHEMBL1688192)
Affinity DataEC50:  6.24E+3nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483545(CHEMBL1688194)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483546(CHEMBL1688195)
Affinity DataEC50:  2.65E+3nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483539(CHEMBL1688184)
Affinity DataEC50:  60nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483541(CHEMBL1688187)
Affinity DataEC50:  430nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483547(CHEMBL1688189)
Affinity DataEC50:  720nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483542(CHEMBL1688190)
Affinity DataEC50:  280nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483544(CHEMBL1688192)
Affinity DataEC50:  3.27E+3nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483545(CHEMBL1688194)
Affinity DataEC50:  1.53E+3nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483547(CHEMBL1688189)
Affinity DataEC50:  500nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483540(CHEMBL1688186)
Affinity DataEC50:  150nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483546(CHEMBL1688195)
Affinity DataEC50:  2.95E+3nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483548(CHEMBL1688185)
Affinity DataEC50:  200nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483549(CHEMBL1688188)
Affinity DataEC50:  840nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483550(CHEMBL1688183)
Affinity DataEC50:  90nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483549(CHEMBL1688188)
Affinity DataEC50:  860nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483543(CHEMBL1688191)
Affinity DataEC50:  360nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483550(CHEMBL1688183)
Affinity DataEC50:  30nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H3 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483548(CHEMBL1688185)
Affinity DataEC50:  320nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50483551(CHEMBL1688193)
Affinity DataEC50:  530nMAssay Description:Inhibition of HDAC activity in human NB4 cells assessed as acetylation of histone H4 after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50124518((E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)...)
Affinity DataEC50:  200nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed