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Found 157 with Last Name = 'sirtori' and Initial = 'fr'
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279340((Z)-2-[(Furan-2-ylmethyl)-amino]-5-[1-(1H-pyrrolo[...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279338((Z)-2-(Benzylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279339((Z)-2-Isopropylamino-5-[1-(1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279285((Z)-2-(Isopropylamino)-5-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279251((Z)-2-[(4-Methylcyclohexyl)amino]-5-(1H-pyrrolo[2,...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279215((Z)-2-[(2-Furylmethyl)amino]-5-(1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279338((Z)-2-(Benzylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Cdk9/cyclinT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279248((Z)-2-[(2-Phenylethyl)amino]-5-(1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279247((Z)-5-[1-(1H-Pyrrolo[2,3-b]pyridin-3-yl)-methylide...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279099((Z)-2-(Benzylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279249((Z)-2-(Cyclohexylamino)-5-(1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279214((Z)-2-((S)-1-Phenyl-ethylamino)-5-[1-(1H-pyrrolo[2...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279281((Z)-5-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-[...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279335(CHEMBL484988 | Z)-2-[(3,3-Dimethylbutyl)amino]-5-(...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424917(CHEMBL2311578)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424919(CHEMBL2315422)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279144((Z)-2-Piperidin-1-yl-5-(1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279372((Z)-2-((S)-1-Phenyl-ethylamino)-5-[1-(1H-pyrrolo[2...)
Affinity DataIC50:  26nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279143((Z)-2-(3-Methylphenyl)-5-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279250((Z)-2-(Cyclopropylamino)-5-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataIC50:  33nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279286((Z)-2-(Pentylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279336((Z)-2-[(2-Hydroxyethyl)amino]-5-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50:  37nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279184((Z)-2-[(3-Chlorobenzyl)amino]-5-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50:  39nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424939(CHEMBL2315430)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424938(CHEMBL2315431)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424942(CHEMBL2315427)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279284((Z)-2-(Ethylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50:  45nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279179((Z)-2-Morpholin-4-yl-5-[1-(1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279142((Z)-2-(4-Methylphenyl)-5-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424941(CHEMBL2315428)
Affinity DataIC50:  48nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279182((Z)-2-[(3-Methylbenzyl)amino]-5-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279060((Z)-2-phenyl-5-(1Hpyrrolo[2,3-b]pyridin-3-ylmethyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424916(CHEMBL2315424)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424918(CHEMBL2315423)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279212((Z)-2-[(3-Bromobenzyl)amino]-5-(1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  55nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424920(CHEMBL2315421)
Affinity DataIC50:  58nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279141((Z)-2-Pyridin-3-yl-5-(1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424937(CHEMBL2315432)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279282((Z)-2-[(cyclohexylmethyl)amino]-5-(1H-pyrrolo[2,3-...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424936(CHEMBL2315433)
Affinity DataIC50:  65nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279181((Z)-2-(2-Methyl-morpholin-4-yl)-5-[1-(1H-pyrrolo[2...)
Affinity DataIC50:  66nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424915(CHEMBL2315425)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424940(CHEMBL2315429)
Affinity DataIC50:  71nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424921(CHEMBL2315420)
Affinity DataIC50:  71nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424884(CHEMBL2315450)
Affinity DataIC50:  71nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279211((Z)-2-[(4-Chlorobenzyl)amino]-5-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50:  86nMAssay Description:Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424883(CHEMBL2315451)
Affinity DataIC50:  88nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424882(CHEMBL2315452)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50279099((Z)-2-(Benzylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50:  95nMAssay Description:Inhibition of Cdk9/cyclinT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424881(CHEMBL2315453)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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