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Found 27 with Last Name = 'vishwase' and Initial = 'g'
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575333(CHEMBL4857063)
Affinity DataIC50:  8nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50:  11nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575332(CHEMBL4869725)
Affinity DataIC50:  14nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575328(CHEMBL4868367)
Affinity DataIC50:  32nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575327(CHEMBL4848840)
Affinity DataIC50:  34nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387265(2,6- Difluoro-N-(2′- methyl-5′-(4-meth...)
Affinity DataIC50:  34nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575326(CHEMBL4868517)
Affinity DataIC50:  50nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575329(CHEMBL4859192)
Affinity DataIC50:  55nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387270(2,6- Difluoro-N-(5-(2- methyl-5-(4- methyl-5-oxo-4...)
Affinity DataIC50:  64nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387269(2- Chloro-N-(5-(5-(5,5- dimethyl-4-oxo-4,5- dihydr...)
Affinity DataIC50:  65nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387261(N-(5′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50:  69nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50:  76nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387266(N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- ...)
Affinity DataIC50:  78nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387272(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  94nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50575336(CHEMBL4753998)
Affinity DataIC50:  119nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387297(US10292981, Example 121)
Affinity DataIC50:  150nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387294(US10292981, Example 78)
Affinity DataIC50:  171nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387281(N-(5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  178nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50:  183nMAssay Description:Inhibition of IL2 in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575330(CHEMBL4872805)
Affinity DataIC50:  227nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387290(N-(5- (5,5-Dimethyl-4,5- dihydroisoxazol-3- yl)-2-...)
Affinity DataIC50:  328nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50:  695nMAssay Description:Inhibition of TNF-alpha in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein orai-2/Stromal interaction molecule 1(Homo sapiens)
Lupin

Curated by ChEMBL
LigandPNGBDBM50575336(CHEMBL4753998)
Affinity DataIC50:  895nMAssay Description:Inhibition of Orai2/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50575334(CHEMBL4863881)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein orai-3/Stromal interaction molecule 1(Homo sapiens)
Lupin

Curated by ChEMBL
LigandPNGBDBM50575335(CHEMBL4570175)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human STIM1/Orai3 expressed in HEK293 cells assessed as reduction in Orai3 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50575335(CHEMBL4570175)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human STIM1/Orai1 expressed in HEK293 cells assessed as reduction in Orai1 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG by FLIPR TETRA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed