TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of GFP-fused Cav3.2-alpha1 (unknown origin) expressed in human tsA-201 cells at holding potential of -110 mV by whole cell patch clamp met...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 537nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 589nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 891nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of GFP-fused Cav3.2-alpha1 (unknown origin) expressed in human tsA-201 cells at holding potential of -110 mV by whole cell patch clamp met...More data for this Ligand-Target Pair
Affinity DataIC50: 9.62E+4nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University
Curated by ChEMBL
South Dakota State University
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Antagonist activity at human CRFR1 expressed in HEK293 cells assessed as inhibition of sauvagine-induced cAMP accumulation by measuring sauvagine EC5...More data for this Ligand-Target Pair