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Found 22 with Last Name = 'fahmy' and Initial = 'h'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50074501(Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50074501(Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276840(CHEMBL4160471)
Affinity DataIC50:  170nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50003912(CHEMBL3235706)
Affinity DataIC50:  245nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50003909(CHEMBL3235700)
Affinity DataIC50:  275nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: <300nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50231512(CHEMBL4077901)
Affinity DataIC50:  340nMAssay Description:Inhibition of GFP-fused Cav3.2-alpha1 (unknown origin) expressed in human tsA-201 cells at holding potential of -110 mV by whole cell patch clamp met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50332956((2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thi...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276841(CHEMBL4161963)
Affinity DataIC50:  447nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50332955((2RS,4R)-2-(1,3-diphenyl-1H-pyrazol-4-yl)thiazolid...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50003910(CHEMBL3235703)
Affinity DataIC50:  537nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50003911(CHEMBL3235705)
Affinity DataIC50:  589nMAssay Description:Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276839(CHEMBL4170184)
Affinity DataIC50:  891nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50332954((2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thi...)
Affinity DataIC50:  940nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human recombinant COX2 after 45 minsMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50231514(CHEMBL4081641)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of GFP-fused Cav3.2-alpha1 (unknown origin) expressed in human tsA-201 cells at holding potential of -110 mV by whole cell patch clamp met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50332954((2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thi...)
Affinity DataIC50:  9.62E+4nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50332955((2RS,4R)-2-(1,3-diphenyl-1H-pyrazol-4-yl)thiazolid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50332956((2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelets COX1 after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276840(CHEMBL4160471)
Affinity DataEC50:  1.10nMAssay Description:Antagonist activity at human CRFR1 expressed in HEK293 cells assessed as inhibition of sauvagine-induced cAMP accumulation by measuring sauvagine EC5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed