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Found 56 with Last Name = 'jiao' and Initial = 'h'
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50269378(CHEMBL447311 | apigenin-4'-O-(2''-O-p-coumaroyl)-b...)
Affinity DataKi:  1.44E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) by competitive Lineweaver-burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataIC50:  0.804nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120396(CHEMBL3617774)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120397(CHEMBL3617773)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120398(CHEMBL3617772)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120393(CHEMBL3617778)
Affinity DataIC50:  35nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120395(CHEMBL3617776)
Affinity DataIC50:  138nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120399(CHEMBL3617771)
Affinity DataIC50:  250nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120394(CHEMBL3617777)
Affinity DataIC50:  465nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50509323(CHEMBL4436622)
Affinity DataIC50:  1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50509324(CHEMBL4463460)
Affinity DataIC50:  1.60E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120401(CHEMBL3617768)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530579(CHEMBL4452883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530581(CHEMBL4444045)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530580(CHEMBL4446933)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530579(CHEMBL4452883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530581(CHEMBL4444045)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530578(CHEMBL4452781)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530581(CHEMBL4444045)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530580(CHEMBL4446933)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530579(CHEMBL4452883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530580(CHEMBL4446933)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530578(CHEMBL4452781)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530578(CHEMBL4452781)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530578(CHEMBL4452781)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530581(CHEMBL4444045)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530581(CHEMBL4444045)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530580(CHEMBL4446933)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530579(CHEMBL4452883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530580(CHEMBL4446933)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530581(CHEMBL4444045)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530578(CHEMBL4452781)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530579(CHEMBL4452883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530579(CHEMBL4452883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530580(CHEMBL4446933)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50530578(CHEMBL4452781)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ACL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50277358(CHEMBL4174432)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50509325(CHEMBL4524936)
Affinity DataIC50:  8.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  9.82E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50509326(CHEMBL4454696)
Affinity DataIC50:  1.00E+4nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120400(CHEMBL3617770)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50537211(CHEMBL4571704)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345577(CHEMBL1782082 | Hippolide A)
Affinity DataIC50:  2.38E+4nMAssay Description:Inhibition of recombinant PTP1B catalytic domain using pNPP as substrate assessed as pNP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50269378(CHEMBL447311 | apigenin-4'-O-(2''-O-p-coumaroyl)-b...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27506(3-AB | 3-aminobenzamide | CHEMBL81977)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345576(CHEMBL1784622 | Hippolide B)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of recombinant PTP1B catalytic domain using pNPP as substrate assessed as pNP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50345578(CHEMBL1784623 | Hippolide E)
Affinity DataIC50:  4.04E+4nMAssay Description:Binding affinity at PKCalpha after 1 hr by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50345577(CHEMBL1782082 | Hippolide A)
Affinity DataIC50:  6.20E+4nMAssay Description:Binding affinity at PKCgamma after 1 hr by luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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