Affinity DataIC50: 2nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Antibacterial activity of the compound against TMP-Resistant Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair