TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Competitive inhibition of human recombinant GST-tagged PTP1B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibitor c...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Binding affinity towards nicotinic receptor in rat brain using [3H]cytisine ligandMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Competitive type inhibition of PTP1B (unknown origin) using pNPP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Competitive type inhibition of PTP1B (unknown origin) using pNPP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human p38alpha expressed in Escherichia coli assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase F227L/V106A double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase E138K mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric anal...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human p38alpha expressed in Escherichia coli assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 35(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Desensitization of GPR35 in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution pretreated for 1 hr followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric anal...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase F227L/V106A double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase E138K mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase E138K mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric anal...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human p38alpha expressed in Escherichia coli assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-AT...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human ERG potassium channel expressed in CHO cells by automated patch clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Yanbian University College Of Pharmacy
Curated by ChEMBL
Yanbian University College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin deoxyuridine triphosphate (biotin-dUTP) incorp...More data for this Ligand-Target Pair
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