Compile Data Set for Download or QSAR
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Found 542 with Last Name = 'buchstaller' and Initial = 'hp'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505332(CHEMBL4567515)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505331(CHEMBL4458129)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505332(CHEMBL4567515)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409634(CHEMBL5274873)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409622(CHEMBL5272750)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505331(CHEMBL4458129)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409634(CHEMBL5274873)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409619(CHEMBL5271127)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409622(CHEMBL5272750)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409619(CHEMBL5271127)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505324(CHEMBL4588170)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409626(CHEMBL5284314)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505332(CHEMBL4567515)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505324(CHEMBL4588170)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505334(CHEMBL4551200)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409618(CHEMBL5281076)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409632(CHEMBL5279709)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505335(CHEMBL4584689)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505334(CHEMBL4551200)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409623(CHEMBL5280682)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409621(CHEMBL5269584)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409620(CHEMBL5275576)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505335(CHEMBL4584689)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409629(CHEMBL5269897)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409621(CHEMBL5269584)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313446(CHEMBL1096003 | N-(((2R,4aS,5R,10bS)-9-chloro-7-fl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409624(CHEMBL5278616)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409632(CHEMBL5279709)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313441(3-(dimethylamino)-N-(((2R,4aS,5R,10bS)-9-isopropyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409623(CHEMBL5280682)
Affinity DataIC50:  2.10nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505325(CHEMBL4450725)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505325(CHEMBL4450725)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409625(CHEMBL5280345)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409618(CHEMBL5281076)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409630(CHEMBL5280167)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409620(CHEMBL5275576)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409624(CHEMBL5278616)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409631(CHEMBL5279214)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409637(CHEMBL5277254)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409629(CHEMBL5269897)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313442(1-((2R,4aS,5R,10bS)-9-bromo-7-fluoro-5-phenyl-3,4,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505327(CHEMBL4586580)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50409628(CHEMBL5276381)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of Neisseria gonorrhoeaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409626(CHEMBL5284314)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50505327(CHEMBL4586580)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50409637(CHEMBL5277254)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
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