TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Binding affinity of the compound against porcine erythrocyte calpain I was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of cathepsin B from human brainMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Compound tested for inhibition of porcine calpain IMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
Affinity DataKi: 41nM ΔG°: -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Binding affinity of the compound against porcine erythrocyte calpain I was determinedMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 63nM ΔG°: -40.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Compound tested for inhibition of porcine Calpain 1More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Compound tested for inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:The compound was evaluated for inhibition of Calpain 1 from porcine erythrocytesMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 74nMAssay Description:Binding affinity of the compound against porcine erythrocyte calpain I was determinedMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Compound tested for inhibition of porcine Calpain 1More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 108nM ΔG°: -39.4kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 119nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibition of cathepsin B from human brainMore data for this Ligand-Target Pair
Affinity DataKi: 128nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
Affinity DataKi: 191nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
Affinity DataKi: 196nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center
Curated by ChEMBL
The University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Compound tested for inhibition of porcine Calpain 1More data for this Ligand-Target Pair
Affinity DataKi: 256nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
Affinity DataKi: 273nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair