Report error Found 187 with Last Name = 'leroy' and Initial = 'j'
Affinity DataKi: 0.300nMAssay Description:Competitive inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Competitive inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 147nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 176nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 256nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase using tritium-labeled glycogen as substrate by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 489nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b in presence of glucose 1-phosphateMore data for this Ligand-Target Pair
Affinity DataKi: 3.11E+3nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.10E+3nMAssay Description:Competitive inhibition of rabbit skeletal muscle glycogen phosphorylase bMore data for this Ligand-Target Pair
Affinity DataKi: 5.97E+4nMAssay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b by Lineweaver-Burk plot analysis in presence of glucose 1-phosphateMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+5nMAssay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b in presence of glucose 1-phosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse recombinant Aurora A kinase expressed in insect Sf9 cells by radioactive flashplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant mouse aurora kinase A expressed in insect Sf9 cells using biotin-GLRRASLG as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of Aurora A Thr288 autophosphorylation in human HeLa cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of aurora kinase A autophosphorylation at T288 in human HCT116 cells by immunofluorescence analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysisMore data for this Ligand-Target Pair