TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Compound was tested for its inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mPGES-1 in human fetal fibroblast cells assessed as PGF2alpha level after 50 mins by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair