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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50057560'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057560(4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057560(4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057560(4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  15.1nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057560(4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  15.1nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed