TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound towards opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity of the compound towards opioid receptor mu 2More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D1 using SCH-23390 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity of the compound towards opioid receptor mu 1More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories
Curated by ChEMBL
Pharm-Eco Laboratories
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI.More data for this Ligand-Target Pair