TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged HDAC6 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human KDM5B expressed in baculovirus expression system using (ARTK(me3)QTARKSTGGKAPRKQLA peptide substMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full-length recombinant human HDAC6 using RHKKAc peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human KDM5B expressed in baculovirus expression system using (ARTK(me3)QTARKSTGGKAPRKQLA peptide substMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-lysine tripeptide substrate as substrate preincubated for 24 hrs followed by substrate addition by ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of N-terminal GST-tagged HDAC6 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc peptide as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant KDM5B (residues 26 to 770) (unknown origin) transfected in Sf9 cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human HDAC6 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human HDAC6 using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of KDM5A (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of N-terminal GST-tagged HDAC1 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of N-terminal GST-tagged HDAC2 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 209nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of N-terminal GST-tagged HDAC3 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 219nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 346nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 353nMAssay Description:Inhibition of KDM5C (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 393nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 414nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 584nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 593nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 712nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 854nMAssay Description:Inhibition of recombinant human HDAC8 using RHKAcKAc peptide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 943nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair