Compile Data Set for Download or QSAR
maximum 50k data
Found 51 with Last Name = 'koglin' and Initial = 'm'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610369(CHEMBL5277174)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of GCase in patient derived fibroblast cells using 5'pentafluorobenzoylaminofluorescein-di-beta-D-glucoside as substrate assessed as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610370(CHEMBL5285901)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of GCase in patient derived fibroblast cells using 5'pentafluorobenzoylaminofluorescein-di-beta-D-glucoside as substrate assessed as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610353(CHEMBL5270898)
Affinity DataIC50:  27nMAssay Description:Inhibition of GCase in patient derived fibroblast cells using 5'pentafluorobenzoylaminofluorescein-di-beta-D-glucoside as substrate assessed as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant GCase (unknown origin) using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at pH 4.5More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  410nMAssay Description:Inhibition of GCase in patient derived fibroblast cells using 5'pentafluorobenzoylaminofluorescein-di-beta-D-glucoside as substrate assessed as subst...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610369(CHEMBL5277174)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant GCase (unknown origin) using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at pH 4.5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610370(CHEMBL5285901)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of recombinant GCase (unknown origin) using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at pH 4.5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610353(CHEMBL5270898)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of recombinant GCase (unknown origin) using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at pH 4.5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610344(CHEMBL5279401)
Affinity DataEC50:  1.40E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610345(CHEMBL5291224)
Affinity DataEC50:  72nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610346(CHEMBL5287219)
Affinity DataEC50:  170nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610347(CHEMBL5287675)
Affinity DataEC50:  100nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610348(CHEMBL5276122)
Affinity DataEC50:  63nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610349(CHEMBL5288960)
Affinity DataEC50:  130nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610350(CHEMBL5276663)
Affinity DataEC50:  70nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610351(CHEMBL5272738)
Affinity DataEC50:  40nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610352(CHEMBL5290073)
Affinity DataEC50:  58nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610353(CHEMBL5270898)
Affinity DataEC50:  9.60nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610354(CHEMBL5268346)
Affinity DataEC50:  5.30E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610355(CHEMBL5266397)
Affinity DataEC50:  6.80E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610356(CHEMBL5272210)
Affinity DataEC50:  7.10E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610357(CHEMBL5287823)
Affinity DataEC50:  360nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610358(CHEMBL5272952)
Affinity DataEC50:  460nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610359(CHEMBL5289722)
Affinity DataEC50:  1.80E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610360(CHEMBL5283330)
Affinity DataEC50:  660nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610361(CHEMBL5279069)
Affinity DataEC50:  2.10E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610362(CHEMBL5270914)
Affinity DataEC50:  680nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610363(CHEMBL5286668)
Affinity DataEC50: >2.50E+4nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610364(CHEMBL5289693)
Affinity DataEC50:  220nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610365(CHEMBL5289154)
Affinity DataEC50:  120nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610366(CHEMBL5290054)
Affinity DataEC50:  250nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610367(CHEMBL5280450)
Affinity DataEC50:  79nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610368(CHEMBL5283935)
Affinity DataEC50:  30nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610369(CHEMBL5277174)
Affinity DataEC50:  5.60nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610370(CHEMBL5285901)
Affinity DataEC50:  6.01E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610371(CHEMBL5267578)
Affinity DataEC50:  540nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610372(CHEMBL5282146)
Affinity DataEC50:  150nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610373(CHEMBL5285193)
Affinity DataEC50:  410nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610374(CHEMBL4561657)
Affinity DataEC50:  90nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataEC50:  300nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610353(CHEMBL5270898)
Affinity DataEC50:  13nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell assessed as GCase level incubated for 5 days by immunocytochemistry a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataEC50:  390nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell assessed as GCase level incubated for 5 days by immunocytochemistry a...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610343(CHEMBL5275563)
Affinity DataEC50:  5.20E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610342(CHEMBL5266290)
Affinity DataEC50:  29nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610341(CHEMBL5278339)
Affinity DataEC50:  170nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610340(CHEMBL5272591)
Affinity DataEC50:  630nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610339(CHEMBL5271587)
Affinity DataEC50:  440nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610338(CHEMBL5265984)
Affinity DataEC50:  150nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))TBA
LigandPNGBDBM50610337(CHEMBL5271750)
Affinity DataEC50:  75nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50035057((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to His-tagged human beta1 adrenergic receptor expressed in HEK293 cell membranes by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 51 total ) | Next | Last >>
Jump to: