TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 autophosphorylation in human AML cells isolated from relapsed acute myeloid leukemia patient by Western blottingMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 9.90nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 165nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 229nMAssay Description:Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair