BDBM50326053 CHEMBL608533::PKC-412::US20240132489, Compound Staurosporine
SMILES CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
InChI Key InChIKey=BMGQWWVMWDBQGC-IIFHNQTCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1157 hits for monomerid = 50326053
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to EPHB1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2.10E+3nMAssay Description:Binding affinity to HPK1More data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Binding affinity to PDGFRAMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to p38-deltaMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to HIPK2More data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Binding affinity to FRKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK4More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to FGFR4More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to NEK2More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MAP3K1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CLK3More data for this Ligand-Target Pair
Affinity DataKd: 420nMAssay Description:Binding affinity to RIOK3More data for this Ligand-Target Pair
Affinity DataKd: 320nMAssay Description:Binding affinity to PRKCDMore data for this Ligand-Target Pair
Affinity DataKd: 48nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding affinity to GSK3BMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to IGF1RMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Binding affinity to FGFR2More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TAOK3More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to FESMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 180nMAssay Description:Binding affinity to AMPK-alpha1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR1More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 950nMAssay Description:Binding affinity to MKNK2More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to EPHB3More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to DYRK2More data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Binding affinity to PDPK1More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to PAK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to NEK6More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MST4More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to WEE2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MEK2More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to DCAMKL2More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA6(Kin.Dom.2-C-terminal)More data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding affinity to KITMore data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMAssay Description:Binding affinity to MERTKMore data for this Ligand-Target Pair
Affinity DataKd: 560nMAssay Description:Binding affinity to SIK2More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PIK3CDMore data for this Ligand-Target Pair
Affinity DataKd: 94nMAssay Description:Binding affinity to JH1 catalytic domain JAK2More data for this Ligand-Target Pair
Affinity DataKd: 48nMAssay Description:Binding affinity to AAK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to BMPR1AMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CDC2L2More data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding affinity to TNK1More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 460nMAssay Description:Binding affinity to AMPK-alpha2More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to CAMK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TYRO3More data for this Ligand-Target Pair
Affinity DataKd: 960nMAssay Description:Binding affinity to PRKXMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CSNK2A2More data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Binding affinity to MARK1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to INSRRMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding affinity to SRPK2More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CDK7More data for this Ligand-Target Pair