Affinity DataKi: 20nMAssay Description:Competitive inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
TargetCytochrome P450 2E1(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-(+)-mephenytoin as substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2E1(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2E1 in human liver microsomes by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Pontif£Cia Universidade Cat£Lica Do Rio Grande Do Sul
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human thymidine phosphorylase expressed in Escherichia coli Rosetta (DE3) cells using thymidine as substrate after 1 min by...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 263nMAssay Description:Binding affinity to human recombinant UP1-inorganic phosphate binary complex expressed in Escherichia coli Rosetta (DE3) by isothermal titration calo...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 4.20E+3nMAssay Description:Binding affinity to human recombinant UP1 expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 1.40E+3nMAssay Description:Binding affinity to human recombinant UP1-inorganic phosphate binary complex expressed in Escherichia coli Rosetta (DE3) by isothermal titration calo...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 108nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 1.40E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 3.80E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 150 uM R1P by isothermal titration calori...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 2.30E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 150 uM R1P by isothermal titration calori...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 7.40E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorim...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 127nMAssay Description:Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 150 uM R1P by isothermal titration calori...More data for this Ligand-Target Pair
TargetUridine phosphorylase 1(Homo sapiens (Human))
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University Of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 502nMAssay Description:Binding affinity to human recombinant UP1-inorganic phosphate binary complex expressed in Escherichia coli Rosetta (DE3) by isothermal titration calo...More data for this Ligand-Target Pair