TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of fluorescently labeled tracer binding to human ERG by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of biotinylated acetylated peptide from poly His-tagged CBP bromodomain (unknown origin) expressed in Escherichia coli BL21(DE3) by Alph...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Displacement of Histone H4 peptide (1-21) K5/8/12/16Ac-Biotin from recombinant human N-terminal His-tagged CBP bromodomain expressed in Escherichia c...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataIC50: 3.36E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...More data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Inhibition of wild-type human ABL2 (A248 to G542 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Inhibition of full-length human EPHB4 expressed in MEF cells assessed as autophosphorylation by sandwitch-ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 360nMAssay Description:Inhibition of full-length human EPHB4 expressed in MEF cells assessed as autophosphorylation by sandwitch-ELISAMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKd: 2.50E+4nMAssay Description:Binding affinity to recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli at 10 degree C by ...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+3nMAssay Description:Displacement of biotinylated acetylated peptide from recombinant human partial length CBP bromodomain (R1081 to G1197 residues) expressed in bacteria...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKd: 9.60E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
Affinity DataKd: 970nMAssay Description:Displacement of biotinylated acetylated peptide from recombinant human partial length CBP bromodomain (R1081 to G1197 residues) expressed in bacteria...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKd: 1.50E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair