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Found 412 with Last Name = 'nguyen' and Initial = 'qn'
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648851(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...)
Affinity DataIC50:  1nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648802(8-(4-cyclopropylpiperazin-1-yl)-N-(1- (methylsulfo...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648802(8-(4-cyclopropylpiperazin-1-yl)-N-(1- (methylsulfo...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648803(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(1- (...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648803(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(1- (...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648803(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(1- (...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648803(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(1- (...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648804(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648804(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648804(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648804(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648805(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(4-(4...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648805(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(4-(4...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648805(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(4-(4...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648806(3-cyclopropyl-1-(2-((1-(methylsulfonyl)piperidin- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648806(3-cyclopropyl-1-(2-((1-(methylsulfonyl)piperidin- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648806(3-cyclopropyl-1-(2-((1-(methylsulfonyl)piperidin- ...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648806(3-cyclopropyl-1-(2-((1-(methylsulfonyl)piperidin- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648807(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(5-(6...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648807(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(5-(6...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648808(N-(1-(methylsulfonyl)piperidin-4-yl)-8-(8-oxa-2- a...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648808(N-(1-(methylsulfonyl)piperidin-4-yl)-8-(8-oxa-2- a...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648808(N-(1-(methylsulfonyl)piperidin-4-yl)-8-(8-oxa-2- a...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648809(8-(6-cyclopropyl-2,6-diazaspiro[3.3]heptan-2-yl)- ...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648810(N-(4-(4-methylpiperazin-1-yl)phenyl)-8-(7- (methyl...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648811(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648811(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648811(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Chelation-En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648813(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648813(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648813(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Chelation-En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648813(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648814(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(8,8- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648814(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(8,8- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648814(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(8,8- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Chelation-En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648814(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(8,8- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648815(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648815(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648815(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648817((3aR,8bR)-2-(2-((1-(methylsulfonyl)piperidin-4- yl...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648817((3aR,8bR)-2-(2-((1-(methylsulfonyl)piperidin-4- yl...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648817((3aR,8bR)-2-(2-((1-(methylsulfonyl)piperidin-4- yl...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648817((3aR,8bR)-2-(2-((1-(methylsulfonyl)piperidin-4- yl...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648818(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648818(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...)
Affinity DataIC50: <200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648818(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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