Affinity DataKi: 740nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 744nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 8.50E+4nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 1.39E+5nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 1.55E+5nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 1.74E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataKi: 3.54E+5nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+5nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+5nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 5.88E+5nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 9.55E+5nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+6nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+6nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 4.74E+6nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 6.22E+6nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 6.38E+6nMAssay Description:In vitro inhibition of angiotensin converting enzyme isolated from rat lung.More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+7nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+7nMAssay Description:In vitro inhibition of Neutral Endopeptidase isolated from rat kidney.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human Nav1.6 alpha expressed in HEK293 cells incubated for 5 mins with 6 consecutive train pulses to -10 mV at 0.1 Hz and holding poten...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human Nav1.6 alpha expressed in HEK293 cells incubated for 5 mins with 6 consecutive train pulses to -10 mV at 0.1 Hz and holding poten...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR3 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged Flt1 using poly(Glu,Tyr) as substrate after 60 mins by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat Nav1.7 stably expressed in cells with train pulses to -20 mV at 0.1 Hz and holding potential of -90 mV by whole-cell QPatch HT assa...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR1 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair