Compile Data Set for Download or QSAR
maximum 50k data
Found 401 with Last Name = 'holvey' and Initial = 'rs'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427143(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)
Affinity DataIC50:  0.490nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427143(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)
Affinity DataIC50:  0.490nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427127(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)
Affinity DataIC50:  0.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427127(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)
Affinity DataIC50:  0.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)
Affinity DataIC50:  0.570nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427196(US10544132, Example 137)
Affinity DataIC50:  0.570nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427156(4-{[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[I-hydroxy-...)
Affinity DataIC50:  0.640nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427156(4-{[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[I-hydroxy-...)
Affinity DataIC50:  0.640nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427123(US10544132, Example 70 | US10981898, Example 69)
Affinity DataIC50:  0.700nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50576730(CHEMBL4869200 | US20230348495, Example 9)
Affinity DataIC50:  0.700nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427122(US10544132, Example 69 | US10981898, Example 70)
Affinity DataIC50:  0.700nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50576728(CHEMBL4849611 | US20230348495, Example 7)
Affinity DataIC50:  0.700nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427147((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  0.790nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427147((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  0.790nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM492987(US10981898, Example 98)
Affinity DataIC50:  0.800nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427098(US10544132, Example 50 | US10981898, Example 62 | ...)
Affinity DataIC50:  0.800nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633148(US20230348495, Example 1)
Affinity DataIC50:  0.800nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427158((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  0.800nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427098(US10544132, Example 50 | US10981898, Example 62 | ...)
Affinity DataIC50:  0.800nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50576729(CHEMBL4876274 | US20230348495, Example 8)
Affinity DataIC50:  0.900nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427136((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427139((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427193(US10544132, Example 134 | US11236047, Example 135)
Affinity DataIC50:  1.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427194(US10544132, Example 135 | US10981898, Example 134 ...)
Affinity DataIC50:  1.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50576726(CHEMBL4872714 | US20230348495, Example 3)
Affinity DataIC50:  1.20nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)
Affinity DataIC50:  1.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)
Affinity DataIC50:  1.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633208(US20230348495, Example 11)
Affinity DataIC50:  1.40nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427125(US10544132, Example 72 | US10981898, Example 72 | ...)
Affinity DataIC50:  1.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427125(US10544132, Example 72 | US10981898, Example 72 | ...)
Affinity DataIC50:  1.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633194(US20230348495, Example 4)
Affinity DataIC50:  1.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM633207(US20230348495, Example 10)
Affinity DataIC50:  1.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50576725(CHEMBL4875572 | US20230348495, Example 2)
Affinity DataIC50:  1.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427086((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427086((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427080(US10544132, Example 35)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427118((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427118((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM492940(US10981898, Example 35 | US11236047, Example 35 | ...)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427185(US10544132, Example 126)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM492938(US10981898, Example 33)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427081( (3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427078(US10544132, Example 33 | US11236047, Example 33 | ...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427184(US10544132, Example 125 | US10981898, Example 126)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427081( (3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427124(US10544132, Example 71 | US10981898, Example 71 | ...)
Affinity DataIC50:  2nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427124(US10544132, Example 71 | US10981898, Example 71 | ...)
Affinity DataIC50:  2nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427116((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  2.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427117((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  2.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM492977(US10981898, Example 79)
Affinity DataIC50:  2.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 401 total ) | Next | Last >>
Jump to: