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Found 4 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM427078'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427078(US10544132, Example 33 | US11236047, Example 33 | ...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427078(US10544132, Example 33 | US11236047, Example 33 | ...)
Affinity DataIC50:  1.90nMAssay Description:Each assay was performed in a final volume of 15 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427078(US10544132, Example 33 | US11236047, Example 33 | ...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427078(US10544132, Example 33 | US11236047, Example 33 | ...)
Affinity DataIC50:  10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent