Affinity DataKi: 3.90nMAssay Description:Binding affinity for Estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of aromatase cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 13.1nMAssay Description:Inhibition of aromatase cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 13.1nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 16.5nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 16.5nMAssay Description:Inhibition of aromatase cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of aromatase cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Apparent inhibition of human placental microsomal aromatase assessed as [C14]estrone/[C14]estradiol formation using 0.075 to 0.515 uM [C14]androstene...More data for this Ligand-Target Pair
Affinity DataKi: 18.9nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Apparent inhibition of human placental microsomal aromatase assessed as [C14]estrone/[C14]estradiol formation using 0.075 to 0.515 uM [C14]androstene...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 39nM ΔG°: -44.0kJ/mole IC50: 79nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 39.5nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 40.2nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 44.5nMAssay Description:Apparent binding affinity for human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Apparent inhibition of human placental microsomal aromatase assessed as [C14]estrone/[C14]estradiol formation using 0.075 to 0.515 uM [C14]androstene...More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Apparent inhibition of human placental microsomal aromatase assessed as [C14]estrone/[C14]estradiol formation using 0.075 to 0.515 uM [C14]androstene...More data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Apparent inhibition of human placental microsomal aromatase assessed as [C14]estrone/[C14]estradiol formation using 0.075 to 0.515 uM [C14]androstene...More data for this Ligand-Target Pair
Affinity DataKi: 74nM ΔG°: -42.3kJ/mole IC50: 90nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 95nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 114nM ΔG°: -41.2kJ/mole IC50: 112nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 220nM ΔG°: -39.5kJ/mole IC50: 210nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -39.2kJ/mole IC50: 520nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 260nM ΔG°: -39.1kJ/mole IC50: 220nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 310nM ΔG°: -38.6kJ/mole IC50: 280nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 680nM ΔG°: -36.6kJ/mole IC50: 770nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 900nM ΔG°: -35.9kJ/mole IC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nM ΔG°: -35.2kJ/mole IC50: 3.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nM ΔG°: -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nM ΔG°: -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nM ΔG°: -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+3nMAssay Description:In vitro inhibition of human placental cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 1.69E+3nM ΔG°: -34.3kJ/mole IC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+3nM ΔG°: -34.1kJ/mole IC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nM ΔG°: -31.8kJ/mole IC50: 4.70E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nM ΔG°: -29.2kJ/mole IC50: 3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nM ΔG°: -29.2kJ/mole IC50: 3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.184nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
The Ohio State University
Curated by ChEMBL
The Ohio State University
Curated by ChEMBL
Affinity DataIC50: 0.351nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.542nMAssay Description:Inhibition of human PKCa using histone H1 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08nMAssay Description:Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.39nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
The Ohio State University
Curated by ChEMBL
The Ohio State University
Curated by ChEMBL
Affinity DataIC50: 1.58nMAssay Description:Inhibition of human PKACA using LCGRTGRRNSI as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
The Ohio State University
Curated by ChEMBL
The Ohio State University
Curated by ChEMBL
Affinity DataIC50: 1.76nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair