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TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataIC50:  3.60nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455856(CHEMBL4218724)
Affinity DataIC50:  7.5nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455865(CHEMBL4211318)
Affinity DataIC50:  10nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455883(CHEMBL4207749)
Affinity DataIC50:  13nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455862(CHEMBL4207527)
Affinity DataIC50:  13nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455881(CHEMBL4204254)
Affinity DataIC50:  13nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455880(CHEMBL4209476)
Affinity DataIC50:  14nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455860(CHEMBL4203695)
Affinity DataIC50:  15nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455864(CHEMBL4203028)
Affinity DataIC50:  18nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455868(CHEMBL4204241)
Affinity DataIC50:  21nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455861(CHEMBL4218853)
Affinity DataIC50:  22nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455879(CHEMBL4205576)
Affinity DataIC50:  26nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455874(CHEMBL4208216)
Affinity DataIC50:  28nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455869(CHEMBL4209696)
Affinity DataIC50:  32nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455859(CHEMBL3780895)
Affinity DataIC50:  32nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455876(CHEMBL4217916)
Affinity DataIC50:  33nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455872(CHEMBL4204591)
Affinity DataIC50:  38nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455863(CHEMBL4204941)
Affinity DataIC50:  39nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455884(CHEMBL4210554)
Affinity DataIC50:  40nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455867(CHEMBL4213678)
Affinity DataIC50:  42nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455858(CHEMBL4210798)
Affinity DataIC50:  44nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455857(CHEMBL4218711)
Affinity DataIC50:  55nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455882(CHEMBL4207176)
Affinity DataIC50:  57nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455870(CHEMBL4210221)
Affinity DataIC50:  63nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455875(CHEMBL4213149)
Affinity DataIC50:  71nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455866(CHEMBL4218982)
Affinity DataIC50:  75nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455877(CHEMBL4210021)
Affinity DataIC50:  83nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198633(CHEMBL3925136)
Affinity DataIC50:  86nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198634(CHEMBL3897925)
Affinity DataIC50:  97nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455878(CHEMBL4210580)
Affinity DataIC50:  123nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455871(CHEMBL4205318)
Affinity DataIC50:  130nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  222nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198637(CHEMBL3939621)
Affinity DataIC50:  224nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198632(CHEMBL3936897)
Affinity DataIC50:  553nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156234(US9018255, L-3a)
Affinity DataIC50:  2.80E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156236(US9018255, 3b)
Affinity DataIC50:  2.90E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156233(US9018255, 3a)
Affinity DataIC50:  3.20E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156235(US9018255, D-3a)
Affinity DataIC50:  3.50E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156238(US9018255, 8b)
Affinity DataIC50:  5.90E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156237(US9018255, 8a)
Affinity DataIC50:  8.60E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198635(CHEMBL68236)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198636(CHEMBL3914943)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50198638(CHEMBL3937997)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of Fluormone ES2 Green from human recombinant full length ERalpha expressed in insect cells measured up to 4 hrs by fluorescence polariz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM50426071(CHEMBL406050 | PX-12 | US9018255, PX-12 | med.2172...)
Affinity DataIC50:  1.54E+4nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataKd:  9nMAssay Description:Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometryMore data for this Ligand-Target Pair
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455876(CHEMBL4217916)
Affinity DataKd:  24nMAssay Description:Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed