Report error Found 136 with Last Name = 'knudson' and Initial = 's'
Affinity DataKi: 0.0510nM ΔG°: -58.7kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
Affinity DataKi: 0.440nM ΔG°: -53.4kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Stony Brook University
Curated by ChEMBL
Stony Brook University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Stony Brook University
Curated by ChEMBL
Stony Brook University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -50.7kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 1.30nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.8kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.8kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 2nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nM ΔG°: -49.5kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 2.70nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 7nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Affinity DataKi: 7.10nM ΔG°: -46.5kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 11nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 11nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 11.9nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 19nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Affinity DataKi: 23.6nM ΔG°: -43.5kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 29.6nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 81.9nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 95.7nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 97nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 149nM ΔG°: -39.0kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Affinity DataKi: 192nM ΔG°: -38.3kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 197nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Stony Brook University
Curated by ChEMBL
Stony Brook University
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 203nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 229nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
Affinity DataKi: 247nM ΔG°: -37.7kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 286nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 289nM ΔG°: -37.3kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
Affinity DataKi: 308nM ΔG°: -37.2kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Affinity DataKi: 311nM ΔG°: -37.1kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Affinity DataKi: 331nM ΔG°: -37.0kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 696nM ΔG°: -35.1kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Affinity DataKi: 789nM ΔG°: -34.8kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 792nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.63E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.26E+3nM ΔG°: -32.2kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NAD+More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nM ΔG°: -30.3kJ/molepH: 8.0 T: 25°CAssay Description:Inhibition constant binding to E-NADHMore data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 9.10E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.01E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.15E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.85E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.25E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 6.70E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Stony Brook University
Curated by ChEMBL
Stony Brook University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of 1 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair