TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: 1.15E+5nMAssay Description:Competitive inhibition of Escherichia coli MurD ligase activity using UDP-N-acetylmuramyl-L-alanine as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.347nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.912nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 417nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 708nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 832nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+3nMAssay Description:Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 7.90E+4nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 43 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 1.06E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 71 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 1.20E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 123 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 2.20E+3nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 9 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 13 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 5.50E+3nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 56 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 2.10E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 4 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 1.11E+5nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 4 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Slovenia National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 9.80E+4nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Tested for the biological activity and selectivity against NK-1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Tested for the biological activity and selectivity against NK-1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Tested for the biological activity and selectivity against NK-1 receptorMore data for this Ligand-Target Pair