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Found 26 with Last Name = 'choi' and Initial = 'si'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50428286(DABRAFENIB | GSK2118436A)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563431(CHEMBL4793723)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM221688(US10568884, Cpd 9 | US9314464, 9 | US9593100, Comp...)
Affinity DataIC50:  4nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563437(Arry-614 | Pexmetinib)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563432(CHEMBL4797100)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563427(CHEMBL4758203)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50173609(CHEMBL363648 | D3RKN_11 | N-[4-(2-Ethyl-4-m-tolyl-...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563436(CHEMBL4741154)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563435(CHEMBL4763666)
Affinity DataIC50:  8nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563430(CHEMBL4779919)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563434(CHEMBL4795144)
Affinity DataIC50:  15nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563433(CHEMBL4756408)
Affinity DataIC50:  22nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563428(CHEMBL4755378)
Affinity DataIC50:  26nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563429(CHEMBL4794140)
Affinity DataIC50:  30nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50552567(CHEMBL4779114)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by HotSpot kinase ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563431(CHEMBL4793723)
Affinity DataIC50:  85nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)
Affinity DataIC50:  89nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563429(CHEMBL4794140)
Affinity DataIC50:  140nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563430(CHEMBL4779919)
Affinity DataIC50:  200nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563427(CHEMBL4758203)
Affinity DataIC50:  210nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563428(CHEMBL4755378)
Affinity DataIC50:  330nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50:  500nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563438(CHEMBL4798964)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  4.23E+3nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed