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TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50273541(CHEMBL516312 | N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3...)
Affinity DataKi:  541nMAssay Description:Binding affinity to biotinylated AAK1 (unknown origin) incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET based binding displacement assayMore data for this Ligand-Target Pair
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50273541(CHEMBL516312 | N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3...)
Affinity DataKi:  1.75E+3nMAssay Description:Binding affinity to biotinylated GAK (unknown origin) incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET based binding displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBMP-2-inducible protein kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50273541(CHEMBL516312 | N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3...)
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity to biotinylated BMP2K (unknown origin) incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET based binding displacement assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 16(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50273541(CHEMBL516312 | N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3...)
Affinity DataKi:  1.19E+4nMAssay Description:Binding affinity to biotinylated STK16 (unknown origin) incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET based binding displacement assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502299(CHEMBL4544854)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM311155((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-cyanop...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM321107((S)-ethyl (8-((2-amino-2,4-dimethylpentyl)oxy)-6H-...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM335593(3-((5-((4-aminopiperidin-1-yl)methyl)pyrrolo[2,1-f...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM279457((R)-1-(5-(7H-pyrrolo[2, 3-d]pyrimidin-4-yl)-1H-ben...)
Affinity DataIC50:  4nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50:  4nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502283(CHEMBL4541962)
Affinity DataIC50:  4.30nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502285(CHEMBL4543869)
Affinity DataIC50:  6nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502308(CHEMBL4442812)
Affinity DataIC50:  9.30nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502304(CHEMBL4483684)
Affinity DataIC50:  19nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538885(CHEMBL4646895)
Affinity DataIC50:  22nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538901(CHEMBL4642467)
Affinity DataIC50:  24nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50445242(CHEMBL3102941)
Affinity DataIC50:  24nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50288800(CHEMBL4172550)
Affinity DataIC50:  39nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538879(CHEMBL4645917)
Affinity DataIC50:  42nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  47nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538876(CHEMBL4642620)
Affinity DataIC50:  71nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502305(CHEMBL4443908)
Affinity DataIC50:  72nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538890(CHEMBL4636314)
Affinity DataIC50:  73nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538887(CHEMBL4643096)
Affinity DataIC50:  83nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538900(CHEMBL4641825)
Affinity DataIC50:  99nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538888(CHEMBL4632903)
Affinity DataIC50:  101nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502289(CHEMBL4444527)
Affinity DataIC50:  108nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538897(CHEMBL4639991)
Affinity DataIC50:  110nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538891(CHEMBL4638602)
Affinity DataIC50:  113nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538886(CHEMBL4632372)
Affinity DataIC50:  118nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538904(CHEMBL4633404)
Affinity DataIC50:  124nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538905(CHEMBL4642058)
Affinity DataIC50:  126nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538892(CHEMBL4640730)
Affinity DataIC50:  132nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538903(CHEMBL4635935)
Affinity DataIC50:  136nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086277(CHEMBL3425876)
Affinity DataIC50:  136nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502307(CHEMBL4454007)
Affinity DataIC50:  149nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502290(CHEMBL4524476)
Affinity DataIC50:  161nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538893(CHEMBL4640641)
Affinity DataIC50:  173nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502302(CHEMBL4474078)
Affinity DataIC50:  184nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502293(CHEMBL4461527)
Affinity DataIC50:  209nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538899(CHEMBL4648802)
Affinity DataIC50:  214nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502288(CHEMBL4561278)
Affinity DataIC50:  230nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538898(CHEMBL4638387)
Affinity DataIC50:  262nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024286(CHEMBL3334981)
Affinity DataIC50:  319nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538895(CHEMBL4648554)
Affinity DataIC50:  364nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538889(CHEMBL4644472)
Affinity DataIC50: >370nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538896(CHEMBL4648514)
Affinity DataIC50: >370nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50538894(CHEMBL4635431)
Affinity DataIC50:  370nMAssay Description:Inhibition of tracer 222 binding to recombinant human GST-tagged GAK (1 to 329 residues) expressed in insect cells incubated for 1 hr by Lanthascreen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502297(CHEMBL4448513)
Affinity DataIC50:  381nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502291(CHEMBL4515873)
Affinity DataIC50:  381nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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