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TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM8485((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...)
Affinity DataIC50:  0.540nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM397412(US9987278, Compound Reference 22)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397413(US9987278, Compound Reference 23)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397414(US9987278, Compound Reference 24)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397415(US9987278, Compound Reference 25)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397416(US9987278, Compound Reference 26)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397417(US9987278, Compound Reference 27)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397418(US9987278, Compound Reference 28)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397419(US9987278, Compound Reference 29)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397420(US9987278, Compound Reference 30)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397422(US9987278, Compound Reference 32)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397424(US9987278, Compound Reference 34)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397425(US9987278, Compound Reference 35)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397426(US9987278, Compound Reference 36)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397427(US9987278, Compound Reference 37)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397428(US9987278, Compound Reference 38)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
LigandPNGBDBM397429(US9987278, Compound Reference 39)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397430(US9987278, Compound Reference 40)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397431(US9987278, Compound Reference 41)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397280(US9987278, Compound Reference 2)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397395(US9987278, Compound Reference 5)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397397(US9987278, Compound Reference 7)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397399(US9987278, Compound Reference 9)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397400(US9987278, Compound Reference 10)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397404(US9987278, Compound Reference 14)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397406(US9987278, Compound Reference 16)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397407(US9987278, Compound Reference 17)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397408(US9987278, Compound Reference 18)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397409(US9987278, Compound Reference 19)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397410(US9987278, Compound Reference 20)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397411(US9987278, Compound Reference 21)
Affinity DataIC50: <1nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063148((R)-2-(Biphenyl-4-sulfonylamino)-N-hydroxy-3-(1H-i...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM8485((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063139((R)-2-[4-(4-Bromo-benzoylamino)-benzenesulfonylami...)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063139((R)-2-[4-(4-Bromo-benzoylamino)-benzenesulfonylami...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063154((R)-2-{4-[2-(4-Bromo-phenyl)-2H-tetrazol-5-yl]-ben...)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063148((R)-2-(Biphenyl-4-sulfonylamino)-N-hydroxy-3-(1H-i...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM397405(US9987278, Compound Reference 15)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397421(US9987278, Compound Reference 31)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397423(US9987278, Compound Reference 33)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397403(US9987278, Compound Reference 13)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397402(US9987278, Compound Reference 12)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397401(US9987278, Compound Reference 11)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397398(US9987278, Compound Reference 8)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397396(US9987278, Compound Reference 6)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397394(US9987278, Compound Reference 4)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397393(US9987278, Compound Reference 3)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM397232(US9987278, Compound Reference 1)
Affinity DataIC50:  5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063137((R)-3-Methyl-2-{4-[2-(4-methylsulfanyl-phenyl)-2H-...)
Affinity DataIC50:  5.90nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063166((R)-3-(1H-Indol-3-yl)-2-(4'-methoxy-biphenyl-4-sul...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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