Affinity DataKi: 0.100nM ΔG°: -58.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -58.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -56.3kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -54.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.920nM ΔG°: -52.4kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-53.4kJ/mole IC50: 10nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-53.4kJ/mole IC50: 15nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -51.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -51.4kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nM ΔG°: -48.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
Affinity DataKi: 12.2nM ΔG°: -47.0kJ/mole IC50: 80nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DataKi: 14.7nM ΔG°: -46.5kJ/mole IC50: 200nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DataKi: 19.1nM ΔG°: -45.8kJ/mole IC50: 200nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 214nM ΔG°: -39.6kJ/mole IC50: 4.00E+3nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 570nM ΔG°: -37.1kJ/mole IC50: 1.00E+4nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataKi: 7.10E+3nMAssay Description:Inhibitory activity against purified HIV-1 protease expressed in E. coli in sensitive fluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:inhibitory activity against purified HIV-1 protease in a standardized spectrophotometric assay expressed in E. coliMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
LinköPing University
Curated by ChEMBL
LinköPing University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:inhibitory activity against purified HIV-1 protease in a standardized spectrophotometric assay expressed in E. coliMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DatapH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DatapH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
Affinity DatapH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair