TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of Eu-NDP-MSH from human MC1R expressed in HEK293T cells after 2 hrs by DELFIA methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Mixed-type inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate by Lineweaver-Burk pl...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Non-competitive inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Mixed-type inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of TC-PTP (unknown origin) using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of recombinant human LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of TC-PTP (unknown origin) using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as increase in accumulation of Hoechst 33342 preincubated for 30 mins followed by Hoechst...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of recombinant human LMW-PTP isoform 2 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of recombinant human LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 4.74E+4nMAssay Description:Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of recombinant human LMW-PTP isoform 2 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human TC-PTP expressed in Escherichia coli TB1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Universidad Aut£Noma Del Estado De Morelos
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human TC-PTP expressed in Escherichia coli TB1More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 415nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 854nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 960nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.03E+3nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.58E+3nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.36E+3nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.60nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.21E+3nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.68E+3nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair