TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I-HEAT from human alpha1D-adrenoreceptor expressed in CHOK1 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I-HEAT from human alpha1A-adrenoreceptor expressed in CHOK1 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Guangzhou Medical University
Curated by ChEMBL
Guangzhou Medical University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [125I-HEAT from human alpha1B-adrenoreceptor expressed in CHOK1 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 125nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 4.20E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: 9.10E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 3(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Nanyang Technological University
Curated by ChEMBL
Nanyang Technological University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Tongji University School Of Medicine
Curated by ChEMBL
Tongji University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of CDK9 (unknown origin) using [33-p]-ATP as substrate incubated for 40 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase RNF114(Homo sapiens)
Tongji University School Of Medicine
Curated by ChEMBL
Tongji University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of RNF114 (unknown origin)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Tongji University School Of Medicine
Curated by ChEMBL
Tongji University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of HMGCR (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Tongji University School Of Medicine
Curated by ChEMBL
Tongji University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 523nMAssay Description:Inhibition of CDK9 (unknown origin) incubated for 1 hr by fluorescent polarisation based assayMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Tongji University School Of Medicine
Curated by ChEMBL
Tongji University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HMGCR (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 8.96E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 9.66E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 9.66E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 3.15E+4nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 minsMore data for this Ligand-Target Pair